Evidence mapPaperPMID 34579112Full record

Trial reportNutrients2021

Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial.

Cassie M Mitchell, Brenda M Davy, Monica A Ponder, Ryan P McMillan, Michael D Hughes, Matthew W Hulver, Andrew P Neilson, Kevin P Davy

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Cassie M MitchellDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, VA 24061, USA.
Brenda M DavyDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, VA 24061, USA.
Monica A PonderTranslational Obesity Research Interdisciplinary Graduate Education Program, Virginia Tech, Blacksburg, VA 24061, USA.
Ryan P McMillanDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, VA 24061, USA.
Michael D HughesDepartment of Food Science and Technology, Virginia Tech, Blacksburg, VA 24060, USA.
Matthew W HulverDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, VA 24061, USA.
Andrew P NeilsonPlants for Human Health Institute, North Carolina Research Campus, North Carolina State University, Kannapolis, NC 28081, USA.ORCID 0000-0001-5497-663X
Kevin P DavyDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, VA 24061, USA.
Virginia Tech · USNational Institute of Diabetes and Digestive and Kidney Diseases · USNorth Carolina State University · US

Funding

NIH HHS R21 HL118668-01A1, R21 HL118668-01A1S1
6 · The paper itself

Abstract

Prediabetes affects 84.1 million adults, and many will progress to type 2 diabetes (T2D). The objective of this proof-of-concept trial was to determine the efficacy of inulin supplementation to improve glucose metabolism and reduce T2D risk. Adults (

Indexed as

Dietary SupplementsPrebioticsDiabetes Mellitus, Type 2FemaleHumansInsulinInsulin ResistanceInulinMaleMiddle AgedPilot ProjectsInsulinInulinPrebioticsdiabetesdietary fibergut microbiotainulinmetabolismprebiotics

Identifiers

PMID34579112
PMCPMC8471706
OpenAlexW3199382937

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.