Evidence map›Paper›PMID 34582575›Full record

Trial reportJournal of pineal research2021

The effect of melatonin on glucose tolerance, insulin sensitivity and lipid profiles after a late evening meal in healthy young males.

Mohammed S Albreiki, Benita Middleton, Shelagh M Hampton

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of pineal research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Circadian nutrition and obesity: timing as a nutritional strategy.Journal of health, population, and nutrition · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Mohammed S AlbreikiDepartment of Biochemistry and Physiology, Centre for Chronobiology, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, UK.ORCID https://orcid.org/0000-0002-1508-5161
Benita MiddletonDepartment of Biochemistry and Physiology, Centre for Chronobiology, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, UK.
Shelagh M HamptonDepartment of Biochemistry and Physiology, Centre for Chronobiology, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, UK.
University of Surrey · GBKhalifa University of Science and Technology · AE

Funding

Abu Dhabi Health Services SEHA
6 · The paper itself

Abstract

The suppression of melatonin by light at night (LAN) has been associated with a disruption of SCN function and biological processes. This study aimed to explore the impact of melatonin on glucose and lipid metabolism before and after a late evening meal. Nine healthy male participants (26 ± 1.3 years, BMI 24.8 ± 0.8 kg/m

Indexed as

Insulin ResistanceMelatoninCircadian RhythmCross-Over StudiesGlucoseHumansLipidsMaleMealsGlucoseLipidsMelatoninglucose toleranceinsulin sensitivitylight at nightmelatoninmetabolismNEFAsTAGs

Identifiers

PMID34582575
PMCPMC9285903
OpenAlexW3201845486

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.