Evidence map›Paper›PMID 34585616›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2021

Skeletal muscle bioenergetic health and function in people living with HIV: association with glucose tolerance and alcohol use.

Danielle E Levitt, Tekeda F Ferguson, Stefany D Primeaux, Jeanette A Zavala, Jameel Ahmed, Richard H Marshall, Liz Simon, Patricia E Molina

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Using Computer Vision Libraries to Streamline Nuclei Quantification.Journal of visualized experiments : JoVE · 2025
    Article
  6. Article
  7. Alcohol Alters Skeletal Muscle Bioenergetic Function: A Scoping Review.International journal of molecular sciences · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Alcohol and Skeletal Muscle in Health and Disease.Alcohol research : current reviews · 2023
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Danielle E LevittComprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana.ORCID 0000-0003-1865-1971
Tekeda F FergusonComprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Stefany D PrimeauxComprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Jeanette A ZavalaDepartment of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Jameel AhmedSection of Cardiology, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Richard H MarshallDepartment of Radiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Liz SimonComprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana.ORCID 0000-0003-4149-3406
Patricia E MolinaComprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana.ORCID 0000-0002-3598-384X
Louisiana State University Health Sciences Center New Orleans · USPennington Biomedical Research Center · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Translational Research/Education ComponentP60AA009803 · NIAAA · LSU HEALTH SCIENCES CENTER · PI PATRICIA E. MOLINA · 2004 to 2026
$42.6M
Translational Genomics CoreP30GM114732 · NIGMS · LSU HEALTH SCIENCES CENTER · PI ZABALETA, JOVANNY · 2015 to 2019
$5.2M
Alcohol & Metabolic Comorbidities in PLWHA; Evidence-Driven InterventionsUH2AA026198 · NIAAA · LSU HEALTH SCIENCES CENTER · PI MOLINA, PATRICIA E. · 2017 to 2018
$391k
Alcohol-induced skeletal muscle dysregulation in SIV/HIV: Mitochondrial-mediated mechanismsF32AA027982 · NIAAA · LSU HEALTH SCIENCES CENTER · PI LEVITT, DANIELLE E · 2019 to 2021
$128k
NIAAA NIH HHS F32 AA027982NIAAA NIH HHS P60 AA009803NIAAA NIH HHS UH2 AA026198NIGMS NIH HHS P30 GM114732NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

At-risk alcohol use is prevalent and increases dysglycemia among people living with human immunodeficiency virus (PLWH). Skeletal muscle (SKM) bioenergetic dysregulation is implicated in dysglycemia and type 2 diabetes. The objective of this study was to determine the relationship between at-risk alcohol, glucose tolerance, and SKM bioenergetic function in PLWH. Thirty-five PLWH (11 females, 24 males, age: 53 ± 9 yr, body mass index: 29.0 ± 6.6 kg/m

Indexed as

Energy MetabolismHIV Long-Term SurvivorsAdultAlcohol DrinkingBiomarkersBlood GlucoseCells, CulturedDiabetes Mellitus, Type 2FemaleHIV InfectionsHumansInsulin ResistanceLouisianaMaleMiddle AgedMitochondria, MuscleBiomarkersBlood Glucosealcoholhuman immunodeficiency virusmitochondriaoxygen consumptionproton leak

Identifiers

PMID34585616
PMCPMC8616628
OpenAlexW3201767226

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.