Evidence map›Paper›PMID 34587328›Full record

Trial reportTropical medicine & international health : TM & IH2021

Protective effect of house screening against indoor Aedes aegypti in Mérida, Mexico: A cluster randomised controlled trial.

Pablo Manrique-Saide, Josué Herrera-Bojórquez, Josué Villegas-Chim, Henry Puerta-Guardo, Guadalupe Ayora-Talavera, Manuel Parra-Cardeña, Anuar Medina-Barreiro, Marypaz Ramírez-Medina, Aylin Chi-Ku, Emilio Trujillo-Peña and 10 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Tropical medicine & international health : TM & IH, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 5 countries.

Pablo Manrique-SaideUnidad Colaborativa para Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
Josué Herrera-BojórquezUnidad Colaborativa para Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
Josué Villegas-ChimUnidad Colaborativa para Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
Henry Puerta-GuardoUnidad Colaborativa para Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
Guadalupe Ayora-TalaveraLaboratorio de Virología, Centro de Investigaciones Regionales 'Dr. Hideyo Noguchi', Universidad Autónoma de Yucatán, Mérida, México.
Manuel Parra-CardeñaLaboratorio de Virología, Centro de Investigaciones Regionales 'Dr. Hideyo Noguchi', Universidad Autónoma de Yucatán, Mérida, México.
Anuar Medina-BarreiroUnidad Colaborativa para Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
Marypaz Ramírez-MedinaUnidad Colaborativa para Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
Aylin Chi-KuUnidad Colaborativa para Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
Emilio Trujillo-PeñaUnidad Colaborativa para Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
Rosa E Méndez-ValesServicios de Salud de Yucatán, Mérida, México.
Hugo Delfín-GonzálezUnidad Colaborativa para Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
María E Toledo-RomaníDepartamento de Epidemiología, Instituto de Medicina Tropical 'Pedro Kourí', La Habana, Cuba.
Roberto BazzaniInternational Development Research Centre of Canada, Regional Office for Latin America and the Caribbean, Montevideo, Uruguay.
Edgardo Bolio-ArceoInstituto Municipal de Planeación, Ayuntamiento de Mérida, Mérida, México.
Hector Gómez-DantésCentro de Investigación en Sistemas de Salud, Instituto Nacional de Salud Pública, Cuernavaca, México.
Azael Che-MendozaUnidad Colaborativa para Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
Norma Pavía-RuzLaboratorio de Hematología, Centro de Investigaciones Regionales 'Dr. Hideyo Noguchi', Universidad Autónoma de Yucatán, Mérida, México.
Oscar D KirsteinDepartment of Environmental Sciences, Emory University, Atlanta, Georgia, USA.
Gonzalo M Vazquez-ProkopecDepartment of Environmental Sciences, Emory University, Atlanta, Georgia, USA.
Autonomous University of Yucatán · MXEmory University · USInstituto de Arqueología-Mérida · ESInstituto de Medicina Tropical “Pedro Kourí” · CUInstituto Nacional de Salud Pública · MXInternational Development Research Centre · CASecretaría de Investigación, Innovación y Educación Superior · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the protective effect of house screening (HS) on indoor Aedes aegypti infestation, abundance and arboviral infection in Merida, Mexico.

methodsIn 2019, we performed a cluster randomised controlled trial (6 control and 6 intervention areas: 100 households/area). Intervention clusters received permanently fixed fiberglass HS on all windows and doors. The study included two cross-sectional entomologic surveys, one baseline (dry season in May 2019) and one post-intervention (PI, rainy season between September and October 2019). The presence and number of indoor Aedes females and blood-fed females (indoor mosquito infestation) as well as arboviral infections with dengue (DENV) and Zika (ZIKV) viruses were evaluated in a subsample of 30 houses within each cluster.

resultsHS houses had significantly lower risk for having Aedes aegypti female mosquitoes (odds ratio [OR] = 0.56, 95% CI 0.33-0.97, p = 0.04) and blood-fed females (OR = 0.53, 95% CI 0.28-0.97, p = 0.04) than unscreened households from the control arm. Compared to control houses, HS houses had significantly lower indoor Ae. aegypti abundance (rate ratio [RR] = 0.50, 95% CI 0.30-0.83, p = 0.01), blood-fed Ae. aegypti females (RR = 0.48, 95% CI 0.27-0.85, p = 0.01) and female Ae. aegypti positive for arboviruses (OR = 0.29, 95% CI 0.10-0.86, p = 0.02). The estimated intervention efficacy in reducing Ae. aegypti arbovirus infection was 71%.

conclusionsThese results provide evidence supporting the use of HS as an effective pesticide-free method to control house infestations with Aedes aegypti and reduce the transmission of Aedes-transmitted viruses such as DENV, chikungunya (CHIKV) and ZIKV.

Indexed as

HousingAedesAnimalsCluster AnalysisCross-Sectional StudiesDengue VirusFemaleHost-Pathogen InteractionsHumansMexicoMosquito ControlZika VirusAedes aegyptiAedes-transmitted virusesarbovirusesHouse screeningMerida

Identifiers

PMID34587328
PMCPMC9298035
OpenAlexW3203864444

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.