Evidence map›Paper›PMID 34590593›Full record

ReviewCurrent oncology (Toronto, Ont.)2021

New Insights into the Biology and Diagnosis of Splenic Marginal Zone Lymphomas.

Marie Donzel, Lucile Baseggio, Juliette Fontaine, Florian Pesce, Hervé Ghesquières, Emmanuel Bachy, Aurélie Verney, Alexandra Traverse-Glehen

Open access · goldAbstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Marie DonzelInstitut de pathologie multi-sites, Hôpital Lyon Sud, Hospices Civils de Lyon, 69310 Pierre Bénite, France.
Lucile BaseggioLaboratoire d'hématologie, Hôpital Lyon Sud, Hospices Civils de Lyon, 69310 Pierre Bénite, France.
Juliette FontaineInstitut de pathologie multi-sites, Hôpital Lyon Sud, Hospices Civils de Lyon, 69310 Pierre Bénite, France.
Florian PesceInstitut de pathologie multi-sites, Hôpital Lyon Sud, Hospices Civils de Lyon, 69310 Pierre Bénite, France.
Hervé GhesquièresINSERM-Unité Mixte de Recherche 1052 CNRS 5286, Team "Clinical and Experimental Models of Lymphomagenesis", UCBL, Cancer Research Center of Lyon, Université Lyon, 69001 Lyon, France.
Emmanuel BachyINSERM-Unité Mixte de Recherche 1052 CNRS 5286, Team "Clinical and Experimental Models of Lymphomagenesis", UCBL, Cancer Research Center of Lyon, Université Lyon, 69001 Lyon, France.
Aurélie VerneyINSERM-Unité Mixte de Recherche 1052 CNRS 5286, Team "Clinical and Experimental Models of Lymphomagenesis", UCBL, Cancer Research Center of Lyon, Université Lyon, 69001 Lyon, France.
Alexandra Traverse-GlehenInstitut de pathologie multi-sites, Hôpital Lyon Sud, Hospices Civils de Lyon, 69310 Pierre Bénite, France.
Hospices Civils de Lyon · FRUniversité Claude Bernard Lyon 1 · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Splenic marginal zone lymphoma (SMZL) is a small B-cell lymphoma, which has been recognized as a distinct pathological entity since the WHO 2008 classification. It classically presents an indolent evolution, but a third of patients progress rapidly and require aggressive treatments, such as immuno-chemotherapy or splenectomy, with all associated side effects. In recent years, advances in the comprehension of SMZL physiopathology have multiplied, thanks to the arrival of new devices in the panel of available molecular biology techniques, allowing the discovery of new molecular findings. In the era of targeted therapies, an update of current knowledge is needed to guide future researches, such as those on epigenetic modifications or the microenvironment of these lymphomas.

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellLymphoma, B-CellSplenic NeoplasmsBiologyHumansSplenectomyTumor Microenvironmentgeneticmolecularreviewsplenic marginal zone lymphoma

Identifiers

PMID34590593
PMCPMC8482189
OpenAlexW3198840476

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.