Evidence map›Paper›PMID 34599658›Full record

ArticleHeart and vessels2022

Prognostic value of infarct-related-lead Tpeak-Tend/QT ratio in patients with ST-segment elevation myocardial infarction.

Yue-E Wu, Lan Ma, Ze-Ping Hu

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Article in Heart and vessels, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Yue-E WuDepartment of Electrocardiogram Diagnosis, The Second Affiliated Hospital, Anhui Medical University, Hefei, 230060, Anhui, China.
Lan MaDepartment of Electrocardiogram Diagnosis, The Second Affiliated Hospital, Anhui Medical University, Hefei, 230060, Anhui, China.
Ze-Ping HuDepartment of Cardiology, The First Affiliated Hospital, Anhui Medical University, Hefei, 230022, Anhui, China. 972753735@qq.com.ORCID http://orcid.org/0000-0003-4591-8547

Funding

Anhui Provincial Postdoctoral Science Foundation 2016B097University Natural Science Research Project of Anhui Province (CN) KJ2019ZD65
6 · The paper itself

Abstract

Tpeak-Tend/QT ratio (Tp-e/QT) in patients with ST-segment elevation myocardial infarction (STEMI) is reportedly associated with major adverse cardiac events (MACEs). However, Tp-e/QT measurement methods are controversial, and few studies have clarified the effect of different Tp-e/QT measures on prognosis. Our study is the first to investigate the advantages of the Tp-e/QT measured by infarct-related-lead method in predicting MACEs during hospitalization and long-term mortality in patients with STEMI. A total of 427 STEMI patients undergoing primary percutaneous coronary intervention (PCI) were included in this study. The Tp-e/QT before PCI was measured by traditional 12-lead method and infarct-related-lead method. Outcomes were tested using comparative statistics, logistic regression, receiver operating characteristic (ROC) curve and Kaplan-Meier survival analysis. There were 62 (14.5%) patients who had MACEs in-hospital. Logistic regression showed that the Tp-e/QT in infarct-related-lead was an independent predictor (p < 0.001). The area under the ROC curve (AUC) of the Tp-e/QT in infarct-related-lead was larger than that in the Tp-e/QT in traditional 12-lead (0.889 vs 0.741), and the optimal cutoff value was 0.32. The three-year survival rate of patients in the infarct-related-lead Tp-e/QT < 0.32 group was better than Tp-e/QT ≥ 0.32 group in Kaplan-Meier survival analysis (93.9 vs 87.0%). When stratified according to infarct-related arteries, the results showed that the common odds ratio of patients in Tp-e/QT ≥ 0.32 group occurred MACEs was 1.562, P = 0.038. The infarct-related-lead Tp-e/QT performed better than the traditional 12-lead Tp-e/QT in predicting poor prognosis.

Indexed as

Percutaneous Coronary InterventionST Elevation Myocardial InfarctionElectrocardiographyHumansPrognosisSurvival RateElevation myocardial infarctionInfarct-related-leadPrognosisST-segmentTpeak–Tend/QT ratioTraditional 12-lead

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.