Evidence map›Paper›PMID 34601312›Full record

ArticleCell calcium2021

PIP

Lorena Brito de Souza, Hwei Ling Ong, Xibao Liu, Indu S Ambudkar

Open access · greenAbstract read
In one paragraph

Article in Cell calcium, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lorena Brito de SouzaSecretory Physiology Section, NIDCR, NIH, Bldg. 10/Room 1N-113, Bethesda, MD 20892, USA.
Hwei Ling OngSecretory Physiology Section, NIDCR, NIH, Bldg. 10/Room 1N-113, Bethesda, MD 20892, USA. Electronic address: ongh@mail.nih.gov.
Xibao LiuSecretory Physiology Section, NIDCR, NIH, Bldg. 10/Room 1N-113, Bethesda, MD 20892, USA.
Indu S AmbudkarSecretory Physiology Section, NIDCR, NIH, Bldg. 10/Room 1N-113, Bethesda, MD 20892, USA. Electronic address: indu.ambudkar@nih.gov.
National Institute of Dental and Craniofacial Research · US

Funding

Molecular Regulaton Calcium Flux In Salivary GlandsZ01DE000438 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI AMBUDKAR, INDU S. · 1987 to 2008
$3.6M
Intramural NIH HHS Z01 DE000438
6 · The paper itself

Abstract

Store-operated calcium entry (SOCE) is triggered by assembly of Orai1 with STIM proteins in ER-PM junctions. Plasma membrane PIP

Indexed as

Actin-Related Protein 2-3 ComplexSeptinsActin CytoskeletonCalciumCell MembraneORAI1 ProteinStromal Interaction Molecule 1Actin-Related Protein 2-3 ComplexCalciumORAI1 ProteinSeptinsStromal Interaction Molecule 1ARP2/3CDC42Cytoskeletal remodelingOrai1PIP(2)SEPT4STIM1Store-operated calcium entry

Identifiers

PMID34601312
PMCPMC12128913
OpenAlexW3201520300

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.