Evidence map›Paper›PMID 34602763›Full record

ArticleJournal of obstetrics and gynaecology of India2021

MOTHER Study: A

Charmila Ayyavoo, Asha Baxi, Gorakh Mandrupkar, Sonia Malik, Jayam Kannan, Deepak Goenka, Nagesh Kumar, Monica Singh, Sharda Kulkarni, Kanchan Murarka Agarwal and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of obstetrics and gynaecology of India, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Charmila AyyavooParvathy Ayyavoo Fertility Centre, Aditi Hospital, 5, Usman Ali Street, TVS Tolgate, Trichy, Tamil Nadu 620020 India.ORCID 0000-0003-4740-2042
Asha BaxiDisha Fertility and Surgical Centre, E-30, Saket Nagar, Indore, Madhya Pradesh 452018 India.
Gorakh MandrupkarMandrupkar Clinic, More Nagar, Near ST Stand, Islampur (Dist- Sangli), Maharashtra 415409 India.
Sonia MalikSouthend Fertility and IVF, Max Smart Super Speciality Hospital, Press Enclave Road, Malviya Nagar, Saket, New Delhi, 110017 India.
Jayam KannanGarbba Rakshambigai Fertility Center, Jayam Hospital, No. 4, 6th Cross Street, United India Colony, Kodambakkam, Chennai, Tamil Nadu 600024 India.
Deepak GoenkaInstitute of Human Reproduction, Bharalumukh, Guwahati, Assam 781009 India.
Nagesh KumarJanani Hospital and IVF Centre, Gandhi Nagar, Tumkur, Karnataka 572101 India.
Monica SinghBhopal Test-Tube-Baby and Endoscopy Centre, E-1/13A, Arera Colony, Near No. 7 Stop, Bhopal, Madhya Pradesh 462016 India.
Sharda KulkarniSiddhilife Assisted Reproduction Center, A Wing 101, First floor, Mrud Kishore Building Dattapada Phatak Road, Off S.V.Road, Borival West Mumbai, 40009 India.
Kanchan Murarka AgarwalInstitute of Human Reproduction, Bharalumukh, Guwahati, Assam 781009 India.
Sonam BaxiDisha Fertility and Surgical Centre, E-30, Saket Nagar, Indore, Madhya Pradesh 452018 India.
Bloom Fertility Centre · INChoithram Hospital and Research Centre · INNational Institute of Pharmaceutical Education and Research · INChirayu Medical College & Hospital · INMax Super Speciality Hospital · INPublic Works Department Buildings and Roads · INSeva Mandir · INTumkur University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe physical characteristics which are known to affect the ovarian reserve are age, body mass index (BMI), occupational exposures, age at menarche and menstrual cycle length. A correlation between different physical characteristics and the ovarian reserve will help to identify areas which need to be tackled to increase the chances of fertility of women in India.

methodsIn this retrospective, observational study, namely the MOTHER Study, data of women between 18 and 45 years of age, attending the selected fertility centers across different states in India were taken for evaluation. Demographic information along with information on factors potentially related to fertility like age of menarche, menstrual cycle length and occupational factors were collected by review of medical records at screening visit. Most recent AMH assay and antral follicle count (AFC) where the subject has not taken any contraceptives 12 months prior to the test were collected.

resultsAge of woman, years of marriage, years of infertility and smoking have shown effect on ovarian reserve testing like AMH and AFC. The other physical characteristics which were evaluated and considered to affect the ovarian reserve like body mass index BMI, occupational exposures, age at menarche and menstrual cycle length have not shown statistically significant correlation.

conclusionAge of woman and years of infertility are inversely proportional to ovarian reserve markers, namely AMH and AFC. Addictions like smoking and alcohol affect ovarian reserve.

Indexed as

AFCAge of womanAMHInfertilityOvarian reserve

Identifiers

PMID34602763
PMCPMC8440784
OpenAlexW3160151359

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.