Evidence map›Paper›PMID 34603753›Full record

ArticleSovremennye tekhnologii v meditsine2021

Asynchronous DNA Replication of Biallelically Expressed Genes in Human Peripheral Blood Lymphocytes as a Prognostic Sign of Cancer.

V V Tsepenko, T G Shkavrova, V N Cherkesov, E V Golub, G F Mikhailova

Open access · diamondAbstract read
In one paragraph

Article in Sovremennye tekhnologii v meditsine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

V V TsepenkoSenior Researcher, Laboratory of Molecular and Genetic Pathology, Department of Clinical Morphology; A. Tsyb Medical Radiological Research Centre - Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 4 Korolev St., Obninsk, 249036, Russia.
T G ShkavrovaSenior Researcher, Laboratory of Molecular and Genetic Pathology, Department of Clinical Morphology; A. Tsyb Medical Radiological Research Centre - Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 4 Korolev St., Obninsk, 249036, Russia.
V N CherkesovHead of the Laboratory for Quality Control of Medical Care; A. Tsyb Medical Radiological Research Centre - Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 4 Korolev St., Obninsk, 249036, Russia.
E V GolubLeading Researcher, Laboratory of Molecular and Genetic Pathology, Department of Clinical Morphology; A. Tsyb Medical Radiological Research Centre - Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 4 Korolev St., Obninsk, 249036, Russia.
G F MikhailovaHead of the Laboratory of Molecular and Genetic Pathology, Department of Clinical Morphology; A. Tsyb Medical Radiological Research Centre - Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 4 Korolev St., Obninsk, 249036, Russia.
Morpho (United States) · USFederal State Budgetary Institution "Center for Expertise and Quality Control of Medical Care" · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MATERIALS AND

methodsThe study was carried out with peripheral blood lymphocytes probed for the

resultsIn the control group, the mean frequency of lymphocytes with asynchronous gene replication (AGR) was 22.0±3.4% for

conclusionThis pilot study on lymphocytes with AGR of

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellDNA ReplicationHumansIn Situ Hybridization, FluorescenceLymphocytesMalePilot ProjectsPrognosisasynchronous DNA replicationAURKAdiagnosis of malignant neoplasmsFISHfluorescence in situ hybridizationperipheral blood lymphocytesTP53

Identifiers

PMID34603753
PMCPMC8482818
OpenAlexW3176696189

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.