Evidence map›Paper›PMID 34604057›Full record

ArticleFrontiers in oncology2021

Genetic Variations of

Foteinos-Ioannis D Dimitrakopoulos, Anna G Antonacopoulou, Anastasia E Kottorou, Melpomeni Kalofonou, Nikolaos Panagopoulos, Dimitrios Dougenis, Thomas Makatsoris, Vasiliki Tzelepi, Angelos Koutras, Haralabos P Kalofonos

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. The association betweenFrontiers in genetics · 2026
    Article
  4. Polymorphisms rs2074292 of theHealth science reports · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Foteinos-Ioannis D DimitrakopoulosDivision of Oncology, Department of Medicine, University of Patras, Patras, Greece.
Anna G AntonacopoulouMolecular Oncology Laboratory, Division of Oncology, Department of Medicine, University of Patras, Patras, Greece.
Anastasia E KottorouMolecular Oncology Laboratory, Division of Oncology, Department of Medicine, University of Patras, Patras, Greece.
Melpomeni KalofonouCentre for Bio-Inspired Technology, Institute of Biomedical Engineering, Imperial College London, London, United Kingdom.
Nikolaos PanagopoulosDepartment of Cardiothoracic Surgery, University of Patras, Patras, Greece.
Dimitrios DougenisDepartment of Cardiothoracic Surgery, University of Patras, Patras, Greece.
Thomas MakatsorisDivision of Oncology, Department of Medicine, University of Patras, Patras, Greece.
Vasiliki TzelepiDepartment of Pathology, University of Patras, Patras, Greece.
Angelos KoutrasDivision of Oncology, Department of Medicine, University of Patras, Patras, Greece.
Haralabos P KalofonosDivision of Oncology, Department of Medicine, University of Patras, Patras, Greece.
University of Patras · GRNIHR Imperial Biomedical Research Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmune system-related receptors CD40 (tumor necrosis factor receptor superfamily member 5), BAFFR (tumor necrosis factor receptor superfamily member 13C), and LTβR (tumor necrosis factor receptor superfamily member 3) play a pivotal role in non-small-cell lung cancer (NSCLC). To further evaluate their role in NSCLC,

methodsThe three selected SNPs were evaluated in 229 NSCLC patients and 299 healthy controls, while CD40, BAFFR, and LTβR protein expression was assessed by immunohistochemistry in 96 tumor specimens from NSCLC patients.

resultsIn total,

conclusionsIn conclusion,

Indexed as

NSCLCprognosisriskrs10849448rs1883832rs7290134SNP

Identifiers

PMID34604057
PMCPMC8484958
OpenAlexW3200471425

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.