Evidence map›Paper›PMID 34604117›Full record

ArticleFrontiers in cellular and infection microbiology2021

Roles and Cellular Localization of GBP2 and NAB2 During the Blood Stage of Malaria Parasites.

Mamoru Niikura, Toshiyuki Fukutomi, Jiro Mitobe, Fumie Kobayashi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mamoru NiikuraDepartment of Infectious Diseases, Kyorin University School of Medicine, Tokyo, Japan.
Toshiyuki FukutomiDepartment of Pharmacology and Toxicology, Kyorin University School of Medicine, Tokyo, Japan.
Jiro MitobeDepartment of Infectious Diseases, Kyorin University School of Medicine, Tokyo, Japan.
Fumie KobayashiDepartment of Environmental Science, School of Life and Environmental Science, Azabu University, Kanagawa, Japan.
Kyorin University · JPAzabu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quality control and export of mRNA by RNA-binding proteins are necessary for the survival of malaria parasites, which have complex life cycles. Nuclear poly(A) binding protein 2 (NAB2), THO complex subunit 4 (THO4), nucleolar protein 3 (NPL3), G-strand binding protein 2 (GBP2) and serine/arginine-rich splicing factor 1 (SR1) are involved in nuclear mRNA export in malaria parasites. However, their roles in asexual and sexual development, and in cellular localization, are not fully understood. In this study using the rodent malaria parasite,

Indexed as

MalariaParasitesAnimalsFemaleMaleNucleocytoplasmic Transport ProteinsRNA-Binding ProteinsNucleocytoplasmic Transport ProteinsRNA-Binding ProteinsexportGBP2malariaNAB2quality controlRNA-binding protein

Identifiers

PMID34604117
PMCPMC8479154
OpenAlexW3199748944

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.