Evidence map›Paper›PMID 34604563›Full record

ArticleHeliyon2021

Safety and effect of Neuroform Atlas stent in the treatment of symptomatic intracranial stenosis: A single-center experience.

Orazio Buonomo, Enricomaria Mormina, Antonio Armando Caragliano, Agostino Tessitore, Antonio Pitrone, Mariano Velo, Marco Cavallaro, Carmela Visalli, Francesca Granata, Carmela Vadalà and 1 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Use of the neuroform atlas for stenting of intracranial atherosclerotic disease: Clinical and angiographic outcomes.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  2. Article
  3. Article
  4. Optional or optimal? off-label stenting for intracranial atherosclerotic stenosis: A scoping review.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  5. Review
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  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Orazio BuonomoDepartment of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Enricomaria MorminaDepartment of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Antonio Armando CaraglianoDepartment of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Agostino TessitoreDepartment of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Antonio PitroneDepartment of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Mariano VeloDepartment of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Marco CavallaroDepartment of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Carmela VisalliDepartment of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Francesca GranataDepartment of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Carmela VadalàDepartment of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Sergio Lucio VinciDepartment of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVascular intracranial stenosis (IS) is a significant cause of acute ischemic stroke (AIS). This single-center study aims to show that symptomatic IS treatment by using the Neuroform Atlas stent (Stryker neurovascular, Kalamazoo, MI, USA) could be effective in reducing vessel stenosis.

methodsTen patients affected by AIS or TIA, in the vascular territory of high-grade intracranial atherosclerotic lesions (>70% of vessel stenosis), older than 18-year-old, were treated by implanting a Neuroform Atlas stent (diameter of 4.5mm in 80% and 4mm in 20%). 70% of the patients underwent pre-stenting intracranial angioplasty.

resultsPatients were between 54.8 and 83 years old (mean 68.46y ± 8.44y), 70% males and 30% females. At admission, 50% of all patients had an AIS and 50% a TIA. Restoration of the stenotic lumen was obtained after the endovascular procedure. The percentage mean of vascular stenosis was 83.7% ± 6.09% before treatment (t0), 52.2% ± 10.42% at the end of treatment (t1) and 46.2% ± 8.28% at the follow-up (t2). The IS percentage mean reduction between t0 and t1 was 31.5% ± 7.31%, and between t1 and t2 was 6% ± 5.47%, t0 and t2 of 37.5% ± 7.38%. Percentage reduction of IS was highly significant between time t0 and t1 (

conclusionsIntracranial stenosis endovascular treatment with Neuroform Atlas stent provides encouraging results, with a statistically significant association between the vascular caliber improvement and the endovascular treatment.

Indexed as

Acute ischemic strokeAtherosclerosisIntracranial stenosisNeuroform Atlas stentTransient ischemic attack

Identifiers

PMID34604563
PMCPMC8473543
OpenAlexW3199238159

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.