ArticleeLife2021
Parallel functional testing identifies enhancers active in early postnatal mouse brain.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 44 citations in OpenAlex.
- An in vivo parallelized reporter assay to uncover tissue-specific splicing regulatory sequences in a multicellular animal.Nucleic acids research · 2026Article
- STARR-CRAAVT: A platform to identify cell type-specific regulatory elements for next-generation gene therapy.iScience · 2026Article
- Enhancer-based gene therapy: a new path for precision medicine.Hereditas · 2026Review
- Profiling the epigenomic landscape of late embryonic and adult mouse hind limb muscles.Scientific reports · 2026Article
- Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo.Nature biotechnology · 2026Article
- Programming human cell type-specific gene expression via an atlas of AI-designed enhancers.bioRxiv : the preprint server for biology · 2025Article
- Lineage-specific regulatory evolution: insights from massively parallel reporter assays.Current opinion in genetics & development · 2025Review
- Projection-TAGs enable multiplex projection tracing and multi-modal profiling of projection neurons.Nature communications · 2025Article
- Massively parallel reporter assays and mouse transgenic assays provide correlated and complementary information about neuronal enhancer activity.Nature communications · 2025Article
- Large-scale discovery of potent, compact and erythroid specific enhancers for gene therapy vectors.Nature communications · 2025Article
- Projection-TAGs enable multiplex projection tracing and multi-modal profiling of projection neurons.bioRxiv : the preprint server for biology · 2025Article
- Just a SNP away: The future ofCell insight · 2025Review
- AnFrontiers in genetics · 2025Article
- HDI-STARR-seq: Condition-specific enhancer discovery in mouse liver in vivo.BMC genomics · 2024Article
- Cis-regulatory elements driving motor neuron-selective viral payload expression within the mammalian spinal cord.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Decoding biology with massively parallel reporter assays and machine learning.Genes & development · 2024Review
- Review
- Hidden secrets of the cancer genome: unlocking the impact of non-coding mutations in gene regulatory elements.Cellular and molecular life sciences : CMLS · 2024Review
- HDI-STARR-seq: Condition-specific enhancer discovery in mouse liver in vivo.bioRxiv : the preprint server for biology · 2024Article
- Decoding polygenic diseases: advances in noncoding variant prioritization and validation.Trends in cell biology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 3 institutions in 1 country.
Jason T Lambert *Department of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.ORCID 0000-0002-0264-9482
Linda Su-Feher *Department of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.ORCID 0000-0002-0660-7925
Karol CichewiczDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.ORCID 0000-0001-5926-3663
Tracy L WarrenDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.ORCID 0000-0001-5125-0868
Iva ZdilarDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.ORCID 0000-0002-0080-3132
Yurong WangDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.
Kenneth J LimDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.
Jessica L HaighDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.ORCID 0000-0002-9518-4003
Sarah J MorseDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.
Cesar P CanalesDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.ORCID 0000-0003-2505-8367
Tyler W StradleighDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.
Erika Castillo PalaciosDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.
Viktoria HaghaniDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.ORCID 0000-0002-3700-4027
Spencer D MossDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.
Hannah ParoliniDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.
Diana QuinteroDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.
Diwash ShresthaDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.
Daniel VogtDepartment of Pediatrics and Human Development, Grand Rapids Research Center, Michigan State University, Grand Rapids, United States.
Leah C ByrneHelen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, United States.
Alex S NordDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, United States.ORCID 0000-0003-4259-7514
University of California, Davis · USGrand Rapids Community College · USUniversity of Pittsburgh · US
Funding
Functional Elucidation of the Sequence-Encoded Regulatory Activity of Enhancers in Vivo in the BrainR35GM119831 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Alexander Nord · 2016 to 2026
$3.9MTraining Program in Biomolecular TechnologyT32GM008799 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI LEACH, J. KENT · 2002 to 2016
$2.4MLearning, Memory, and Plasticity (LaMP) Training ProgramT32MH112507 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Karen Zito · 2017 to 2026
$2.4MNIGMS NIH HHS R35 GM119831NIGMS NIH HHS T32 GM008799NIMH NIH HHS T32 MH112507
Abstract
Enhancers are
Indexed as
Enhancer Elements, GeneticAnimalsBrainHigh-Throughput Nucleotide SequencingMiceenhancergeneticsgenomicsmouseMPRAneurodevelopmentneuroscience
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.