Evidence map›Paper›PMID 34608570›Full record

ArticleBiological trace element research2022

Evaluation of Serum Trace Element Levels and Biochemical Parameters of COVID-19 Patients According to Disease Severity.

Omer Faruk Kocak, Fatma Betul Ozgeris, Emine Parlak, Yucel Kadıoglu, Neslihan Yuce, Mehmet Emrah Yaman, Ebubekir Bakan

Abstract read
In one paragraph

Article in Biological trace element research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Zinc and selenium status in coronavirus disease 2019.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. COVID-19 Oral Sequelae: Persistent Gustatory and Saliva Secretory Dysfunctions after Recovery from COVID-19.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Omer Faruk KocakDepartment of Chemical Technology, Erzurum Vocational Training College, Ataturk University, Erzurum, Turkey, 25240. omer.kocak@atauni.edu.tr.
Fatma Betul OzgerisDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Atatürk University, Erzurum, Turkey, 25240.
Emine ParlakDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Atatürk University, Erzurum, Turkey, 25240.
Yucel KadıogluDepartment of Analytical Chemistry, Faculty of Pharmacy, Atatürk University, Erzurum, Turkey, 25240.
Neslihan YuceDepartment of Biochemistry, Faculty of Medicine, Ataturk University, Erzurum, Turkey, 25240.
Mehmet Emrah YamanDepartment of Analytical Chemistry, Faculty of Pharmacy, Atatürk University, Erzurum, Turkey, 25240.
Ebubekir BakanDepartment of Biochemistry, Faculty of Medicine, Ataturk University, Erzurum, Turkey, 25240.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the COVID-19 disease progresses mildly or asymptomatically in some people, its progression is severe and symptomatic in others, and it is an issue that requires a scientific response regarding the disease. The present study includes 60 people infected with COVID-19, and the cases were divided into the following groups: asymptomatic, mild, moderate, and severe. Serum Zn, Se, and Cu levels of these groups were analyzed by ICP-MS. All measurements in the patients were compared with those of 32 healthy individuals. When the patient group is compared with the control group, the serum Zn and Se concentrations were statistically low (p < 0.001) in the patient group. Serum Zn level decreased significantly in 4 different patient groups compared to the control group. Although the serum Se level decreased in all four patient groups compared to the control group, the change in Se level was statistically significant only in the severe and mild patient groups. This study examined serum Zn, Se concentrations, and biochemical parameters in patients with different severity of COVID-19, compared them with healthy individuals, and revealed new targets for diagnosis and treatment by revealing those data that may be important.

Indexed as

COVID-19Trace ElementsCopperHumansSeverity of Illness IndexZincCopperTrace ElementsZincBiochemical parametersCOVID-19ICP-MSTrace elements

Identifiers

PMID34608570
PMCPMC8489790

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.