Evidence map›Paper›PMID 34613399›Full record

SynthesisJournal of the American Medical Informatics Association : JAMIA2021

Extracting social determinants of health from electronic health records using natural language processing: a systematic review.

Braja G Patra, Mohit M Sharma, Veer Vekaria, Prakash Adekkanattu, Olga V Patterson, Benjamin Glicksberg, Lauren A Lepow, Euijung Ryu, Joanna M Biernacka, Al'ona Furmanchuk and 12 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of the American Medical Informatics Association : JAMIA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Biopsychosocial and Environmental Factors That Impact Brain-Gut-Microbiome Interactions in Obesity.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Pooled it
  2. Geo-Enabling Public Health: A Systematic Review of GIS Applications.Advances in experimental medicine and biology · 2026
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
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  7. Artificial intelligence for personalized multiple micronutrient supplementation in maternal health.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Review
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  14. Observational
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  16. Multimodal Training to Unimodal Deployment: Leveraging Unstructured Data During Training to Optimize Structured Data Only Deployment.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026
    Article
  17. SDoH-GPT: using large language models to extract social determinants of health.Journal of the American Medical Informatics Association : JAMIA · 2026
    Article
  18. Article
  19. Article
  20. Article

74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Braja G PatraDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0003-2997-5314
Mohit M SharmaDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0003-0091-5510
Veer VekariaDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0001-9801-2250
Prakash AdekkanattuInformation Technologies and Services, Weill Cornell Medicine, New York, New York, USA.
Olga V PattersonDepartment of Internal Medicine, Division of Epidemiology, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0002-8717-5975
Benjamin GlicksbergIcahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0003-4515-8090
Lauren A LepowIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Euijung RyuDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Joanna M BiernackaDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Al'ona FurmanchukNorthwestern University, Chicago, Illinois, USA.
Thomas J GeorgeDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, Florida, USA.ORCID 0000-0002-6249-9180
William HoganDivision of Hematology & Oncology, Department of Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA, and.ORCID 0000-0002-9881-1017
Yonghui WuDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, Florida, USA.
Xi YangDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, Florida, USA.
Jiang BianDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, Florida, USA.ORCID 0000-0002-2238-5429
Myrna WeissmanVagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Priya WickramaratneVagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
J John MannVagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Mark OlfsonVagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Thomas R CampionDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0001-7624-769X
Mark WeinerDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0001-5586-9940
Jyotishman PathakDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0002-4856-410X

Funding

Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI MILDA Renne SAUNDERS · 2011 to 2026
$10.0M
National Infrastructure for Standardized and Portable EHR Phenotyping AlgorithmsR01GM105688 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI LUO, YUAN, PATHAK, JYOTISHMAN · 2013 to 2020
$5.7M
Linking VA and non-VA data to study the risk of suicide in chronic pain patients.R01MH121907 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI OSLIN, DAVID W., PATHAK, JYOTISHMAN · 2020 to 2024
$3.6M
Using claims data to study the association between Alzheimer's disease and suicidal behaviorsR01MH119177 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI PATHAK, JYOTISHMAN · 2019 to 2022
$3.3M
4/4: Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disordersR01MH121922 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI PATHAK, JYOTISHMAN · 2019 to 2023
$2.0M
2/4: Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disordersR01MH121924 · NIMH · MAYO CLINIC ROCHESTER · PI BIERNACKA, JOANNA M · 2019 to 2024
$2.0M
City Tech-WCM Big Data Training Program in Biomedical InformaticsR25MD011713 · NIMHD · NEW YORK CITY COLLEGE OF TECHNOLOGY · PI GIANNOPOULOU, EVGENIA, PATHAK, JYOTISHMAN · 2017 to 2020
$1.1M
Risk modeling and shared decision making for postpartum depressionR41MH124581 · NIMH · IRIS OB HEALTH INC. · PI LASKOFF, MICHAEL B., PATHAK, JYOTISHMAN · 2021 to 2022
$1.0M
NIDDK NIH HHS P30 DK092949NIGMS NIH HHS R01 GM105688NIH HHS R01MH119177NIMHD NIH HHS R25 MD011713NIMH NIH HHS R01 MH119177NIMH NIH HHS R01 MH121907NIMH NIH HHS R01 MH121922NIMH NIH HHS R01 MH121924NIMH NIH HHS R41 MH124581
6 · The paper itself

Abstract

objectiveSocial determinants of health (SDoH) are nonclinical dispositions that impact patient health risks and clinical outcomes. Leveraging SDoH in clinical decision-making can potentially improve diagnosis, treatment planning, and patient outcomes. Despite increased interest in capturing SDoH in electronic health records (EHRs), such information is typically locked in unstructured clinical notes. Natural language processing (NLP) is the key technology to extract SDoH information from clinical text and expand its utility in patient care and research. This article presents a systematic review of the state-of-the-art NLP approaches and tools that focus on identifying and extracting SDoH data from unstructured clinical text in EHRs. MATERIALS AND

methodsA broad literature search was conducted in February 2021 using 3 scholarly databases (ACL Anthology, PubMed, and Scopus) following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A total of 6402 publications were initially identified, and after applying the study inclusion criteria, 82 publications were selected for the final review.

resultsSmoking status (n = 27), substance use (n = 21), homelessness (n = 20), and alcohol use (n = 15) are the most frequently studied SDoH categories. Homelessness (n = 7) and other less-studied SDoH (eg, education, financial problems, social isolation and support, family problems) are mostly identified using rule-based approaches. In contrast, machine learning approaches are popular for identifying smoking status (n = 13), substance use (n = 9), and alcohol use (n = 9).

conclusionNLP offers significant potential to extract SDoH data from narrative clinical notes, which in turn can aid in the development of screening tools, risk prediction models, and clinical decision support systems.

Indexed as

Electronic Health RecordsNatural Language ProcessingData ManagementHumansMachine LearningSocial Determinants of Healthelectronic health recordsinformation extractionmachine learningnatural language processingpopulation health outcomessocial determinants of health

Identifiers

PMID34613399
PMCPMC8633615

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.