Evidence map›Paper›PMID 34613784›Full record

ArticleMolecular biology of the cell2021

L-bodies are RNA-protein condensates driving RNA localization in

Christopher R Neil, Samantha P Jeschonek, Sarah E Cabral, Liam C O'Connell, Erin A Powrie, Jessica P Otis, Timothy R Wood, Kimberly L Mowry

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. How germ granules promote germ cell fate.Nature reviews. Genetics · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Germ granules in development.Development (Cambridge, England) · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christopher R NeilDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI 02912.
Samantha P JeschonekDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI 02912.
Sarah E CabralDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI 02912.
Liam C O'ConnellDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI 02912.
Erin A PowrieDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI 02912.
Jessica P OtisDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI 02912.
Timothy R WoodDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI 02912.
Kimberly L MowryDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI 02912.

Funding

TRAINING IN MOLECULAR &CELL BIOLOGY &BIOCHEMISTRYT32GM007601 · NIGMS · BROWN UNIVERSITY · PI MOWRY, KIMBERLY L. · 1985 to 2019
$6.4M
COBRE Center for Cancer Research DevelopmentP30GM110759 · NIGMS · RHODE ISLAND HOSPITAL · PI RAMRATNAM, BHARAT · 2015 to 2019
$6.3M
RNA Localization in Xenopus OocytesR01GM071049 · NIGMS · BROWN UNIVERSITY · PI MOWRY, KIMBERLY L. · 2005 to 2018
$4.2M
NIGMS NIH HHS P30 GM110759NIGMS NIH HHS R01 GM071049NIGMS NIH HHS T32 GM007601
6 · The paper itself

Abstract

Ribonucleoprotein (RNP) granules are membraneless compartments within cells, formed by phase separation, that function as regulatory hubs for diverse biological processes. However, the mechanisms by which RNAs and proteins interact to promote RNP granule structure and function in vivo remain unclear. In

Indexed as

AnimalsBiological TransportBiomolecular CondensatesCytoplasmic GranulesOocytesOrganellesRibonucleoproteinsRNARNA, MessengerXenopus laevisRibonucleoproteinsRNARNA, Messenger

Identifiers

PMID34613784
PMCPMC8694076

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.