ReviewJVS-vascular science2021
Review of imaging biomarkers for the vulnerable carotid plaque.
Review in JVS-vascular science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 58 citations in OpenAlex.
- Plaque-Level Machine Learning Prediction of Intraplaque Hemorrhage in Carotid Arteries Using Computed Tomography Angiography.Clinical neuroradiology · 2026Article
- Spectral CT parameters of perivascular adipose tissue as non-invasive biomarkers for identifying symptomatic carotid atherosclerosis.Insights into imaging · 2026Article
- Carotid Perivascular Adipose Tissue Density as a Marker of Large Artery Atherosclerotic Stroke in Patients Undergoing Mechanical Thrombectomy for Acute Middle Cerebral Artery Occlusion.Journal of clinical medicine · 2026Article
- Carotid Atherosclerosis in Chronic Kidney Disease: Pathophysiological Mechanisms, Prevention and Tailored Clinical Management.Journal of clinical medicine · 2026Review
- Geometric and density relationships of calcification clusters in carotid atherosclerosis.The neuroradiology journal · 2026Article
- Prognostic value of plaque burden on computed tomography angiography in patients with symptomatic carotid artery disease.European stroke journal · 2026Article
- Distribution of high-resolution magnetic resonance imaging -based carotid Plaque-RADS subtypes among patients with acute cerebral infarction.Neuroradiology · 2026Article
- Multidimensional clustering of clinical, metabolic, and ultrasound features for 30-day mortality risk stratification in ischemic stroke patients with carotid atherosclerotic plaque.Frontiers in neurology · 2026Article
- Carotid atherosclerotic lesion analysis in 3D based on distance encoding in mesh representation.International journal of computer assisted radiology and surgery · 2025Article
- Superiority of black-blood computed tomography over conventional computed tomography angiography in the identification of soft plaques: a prospective study.Quantitative imaging in medicine and surgery · 2025Article
- Classification of carotid artery plaques: promising alternative methods to computed tomography angiography through radiomics approach using neck non-contrast computed tomography.Quantitative imaging in medicine and surgery · 2025Article
- Carotid artery segmentation in computed tomography angiography (CTA) using multi-scale deep supervision with Swin-UNet and advanced data augmentation.Quantitative imaging in medicine and surgery · 2025Article
- Symptomatic Cervical Carotid Artery Stenosis: Evolving Paradigms in Risk Stratification and Intervention.Annals of Indian Academy of Neurology · 2025Article
- An Artificial Intelligence-Based Non-Invasive Approach for Cardiovascular Disease Risk Stratification in Obstructive Sleep Apnea Patients: A Narrative Review.Reviews in cardiovascular medicine · 2024Review
- Multiscale optoacoustic assessment of skin microvascular reactivity in carotid artery disease.Photoacoustics · 2024Article
- Pericarotid Fat as a Marker of Cerebrovascular Risk.AJNR. American journal of neuroradiology · 2024Review
- Machine Learning Detects Symptomatic Plaques in Patients With Carotid Atherosclerosis on CT Angiography.Circulation. Cardiovascular imaging · 2024Article
- Photon-Counting Computed Tomography in Atherosclerotic Plaque Characterization.Diagnostics (Basel, Switzerland) · 2024Review
- UltraAIGenomics: Artificial Intelligence-Based Cardiovascular Disease Risk Assessment by Fusion of Ultrasound-Based Radiomics and Genomics Features for Preventive, Personalized and Precision Medicine: A Narrative Review.Reviews in cardiovascular medicine · 2024Review
- The Prepetrous Segment of the Internal Carotid Artery as a Neglected Site of Symptomatic Atherosclerosis: A Single-Center Series.Journal of clinical medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Identification of carotid artery atherosclerosis is conventionally based on measurements of luminal stenosis. However, histopathologic studies demonstrate considerable differences between plaques with identical degrees of stenosis and indicate that certain plaque features are associated with increased risk for ischemic events. As a result of the rapid technological evolution in medical imaging, several important steps have been taken in the field of carotid plaque imaging allowing us to visualize the carotid atherosclerotic plaque and its composition in great detail. For computed tomography, magnetic resonance imaging, positron emission tomography, and ultrasound scan, evidence has accumulated on novel imaging-based markers that confer information on carotid plaque vulnerability, such as intraplaque hemorrhage and lipid-rich necrotic cores. In terms of the imaging-based identification of individuals at high risk of stroke, routine assessments of such imaging markers are the way forward for improving current clinical practice. The current review highlights the main characteristics of the vulnerable plaque indicating their role in the etiology of ischemic stroke as identified by intensive plaque imaging.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.