Evidence map›Paper›PMID 34622160›Full record

ArticleiScience2021

caAtlas: An immunopeptidome atlas of human cancer.

Xinpei Yi, Yuxing Liao, Bo Wen, Kai Li, Yongchao Dou, Sara R Savage, Bing Zhang

Abstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Review
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  15. Review
  16. A pan-cancer atlas of therapeutic T cell targets.bioRxiv : the preprint server for biology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xinpei YiLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.
Yuxing LiaoLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.
Bo WenLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.
Kai LiLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.
Yongchao DouLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.
Sara R SavageLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.
Bing ZhangLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.

Funding

iPGDAC, An Integrative Proteogenomic Data Analysis Center for CPTACU24CA210954 · NCI · BAYLOR COLLEGE OF MEDICINE · PI ZHANG, BING · 2016 to 2020
$4.9M
Proteogenomics-driven therapeutic discovery in hepatocellular carcinomaR01CA245903 · NCI · BAYLOR COLLEGE OF MEDICINE · PI ZHANG, BING · 2020 to 2024
$1.0M
NCI NIH HHS R01 CA245903NCI NIH HHS U24 CA210954
6 · The paper itself

Abstract

Comprehensive characterization of tumor antigens is essential for the design of cancer immunotherapies, and mass spectrometry (MS)-based immunopeptidomics enables high-throughput identification of major histocompatibility complex (MHC)-bound peptide antigens

Indexed as

CancerImmunologyProteomics

Identifiers

PMID34622160
PMCPMC8479791

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.