Evidence map›Paper›PMID 34631679›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Laminin-1 Peptides Conjugated to Fibrin Hydrogels Promote Salivary Gland Regeneration in Irradiated Mouse Submandibular Glands.

Kihoon Nam, Harim T Dos Santos, Frank Maslow, Bryan G Trump, Pedro Lei, Stelios T Andreadis, Olga J Baker

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Salivary Gland Bioengineering.Bioengineering (Basel, Switzerland) · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kihoon NamBond Life Sciences Center, University of Missouri, Columbia, MO, United States.
Harim T Dos SantosBond Life Sciences Center, University of Missouri, Columbia, MO, United States.
Frank MaslowBond Life Sciences Center, University of Missouri, Columbia, MO, United States.
Bryan G TrumpSchool of Dentistry, University of Utah, Salt Lake City, UT, United States.
Pedro LeiDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, United States.
Stelios T AndreadisDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, United States.
Olga J BakerBond Life Sciences Center, University of Missouri, Columbia, MO, United States.
University of Missouri · USUniversity at Buffalo, State University of New York · USUniversity of Utah · US

Funding

THE USE OF FIBRIN HYDROGELS TO PROMOTE SALIVARY GLAND REGENERATIONR01DE022971 · NIDCR · UNIVERSITY OF UTAH · PI ANDREADIS, STELIOS T., BAKER, OLGA JULIANA · 2012 to 2025
$7.2M
NIDCR NIH HHS R01 DE022971
6 · The paper itself

Abstract

Previous studies demonstrated that salivary gland morphogenesis and differentiation are enhanced by modification of fibrin hydrogels chemically conjugated to Laminin-1 peptides. Specifically, Laminin-1 peptides (A99: CGGALRGDN-amide and YIGSR: CGGADPGYIGSRGAA-amide) chemically conjugated to fibrin promoted formation of newly organized salivary epithelium both

Indexed as

biomaterialhydrogelirradiated salivary glandsregenerationsalivatissue engineering

Identifiers

PMID34631679
PMCPMC8498954
OpenAlexW3202122521

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.