Evidence map›Paper›PMID 34631832›Full record

ArticleFrontiers in cardiovascular medicine2021

Mitochondrial Respiration Defects in Single-Ventricle Congenital Heart Disease.

Xinxiu Xu, Jiuann-Huey Ivy Lin, Abha S Bais, Michael John Reynolds, Tuantuan Tan, George C Gabriel, Zoie Kondos, Xiaoqin Liu, Sruti S Shiva, Cecilia W Lo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Coenzyme QInternational journal of molecular sciences · 2026
    Article
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  3. Article
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  5. Review
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  7. Article
  8. Article
  9. Medical Therapies for Heart Failure in Hypoplastic Left Heart Syndrome.Journal of cardiovascular development and disease · 2022
    Article
  10. Review
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xinxiu XuDepartment of Developmental Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Jiuann-Huey Ivy LinDepartment of Developmental Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Abha S BaisDepartment of Developmental Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Michael John ReynoldsSchool of Medicine, Pittsburgh Heart, Lung, Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, United States.
Tuantuan TanDepartment of Developmental Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
George C GabrielDepartment of Developmental Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Zoie KondosDepartment of Developmental Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Xiaoqin LiuDepartment of Developmental Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Sruti S ShivaSchool of Medicine, Pittsburgh Heart, Lung, Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, United States.
Cecilia W LoDepartment of Developmental Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
University of Pittsburgh · US

Funding

Cellular Approaches to Tissue Engineering/RegenerationT32EB001026 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DUNCAN, ANDREW W, MONGA, SATDARSHAN SINGH · 2003 to 2024
$5.5M
NIBIB NIH HHS T32 EB001026
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Fontanheart failurehypoplastic left heart syndrome (HLHS)maximal respiratory capacityoxygen consumption rate (OCR)peripheral blood mononuclear cells (PBMC)reserve OCRsingle ventricle congenital heart disease (SV-CHD)

Identifiers

PMID34631832
PMCPMC8494974
OpenAlexW3204197679

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.