ReviewJournal of immunology research2021
HIV-Related Immune Activation and Inflammation: Current Understanding and Strategies.
Review in Journal of immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06935838 (Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV), which is not on this map. Cited by 138 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV
Who cites it
138 citing papers in PubMed, 4 syntheses or guidelines pooled it, 193 citations in OpenAlex.
- Associations Between Depressive Symptoms and Memory Functions in Persons with HIV: A Systematic Review and Meta-Analysis.Neuropsychology review · 2026Pooled it
- Telomere length dynamics in adults living with HIV: A systematic review.BMC infectious diseases · 2026Pooled it
- Pooled it
- High-sensitivity C-reactive protein among people living with HIV on highly active antiretroviral therapy: a systemic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- The Effects of High-Dose Probiotic Supplementation on Immune Activation and Neurocognitive Disorders in People Living with HIV Undergoing Successful Antiretroviral Treatment: The Procog Study.Pathogens (Basel, Switzerland) · 2025Trial
- Trial
- Attenuation of HIV-specific T cell responses Among people with HIV on ART following dipyridamole treatment.Journal of leukocyte biology · 2024Trial
- Stroke in people living with HIV and 6-month outcomes in Northwestern Tanzania.Equity neuroscience · 2026Article
- Development of an investigational medicinal stem cell gene therapy product to attempt curing human immunodeficiency virus infection.Scientific reports · 2026Article
- Identification of distinct HIV reservoir phenotypes and associated immune landscapes.JCI insight · 2026Article
- Association Between Ultra-Processed Food Consumption and Lymphocyte Profile in People Living with HIV: A Cross-Sectional Study.Medical sciences (Basel, Switzerland) · 2026Article
- Targeting NF-κB signaling for HIV latency reversal: Mechanisms, challenges, and therapeutic perspectives.Virus research · 2026Review
- CircRNA profiles of extracellular vesicle-enriched fractions from ART suppressed pregnant women living with HIV identifies interactome networks key to inflammation and viral latency.Journal of translational medicine · 2026Article
- Association Between Chronic Inflammation, Bone Density, and Muscle in Peripubertal Adolescents With and Without HIV in Zimbabwe: A Cross-sectional Study.Open forum infectious diseases · 2026Article
- HIV-driven virome dysbiosis unveils distinct virome features and inter-viral correlations in blood and respiratory niches.Communications biology · 2026Article
- Epigenetic Age Acceleration Is Associated With HIV Infection Independently of Inflammation.Open forum infectious diseases · 2026Article
- Article
- Inflammation and RONS Dysregulation by Redox Enzymes as Mechanistic Links in HIV-1-Cancer Comorbidity.Pathogens (Basel, Switzerland) · 2026Review
- Successful multidisciplinary management of non-muscle-invasive upper tract urothelial carcinoma in a patient with HIV and concurrent staghorn calculus: a case report.AIDS research and therapy · 2026Article
- Epigenetic age acceleration and mortality among persons with poorly controlled HIV.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
78 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although antiretroviral therapy effectively controls human immunodeficiency virus (HIV) replication, a residual chronic immune activation/inflammation persists throughout the disease. This aberrant immune activation and inflammation are considered an accelerator of non-AIDS-related events and one of the driving forces of CD4
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.