ArticleJournal of Zhejiang University. Science. B2021
Evaluation of the prognostic ability of serum uric acid for elderly acute coronary syndrome patients with diabetes mellitus: a prospective cohort study.
Article in Journal of Zhejiang University. Science. B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Association of uric acid with all-cause mortality in acute coronary syndrome patients with T2DM.Atherosclerosis plus · 2025Article
- Perforation of the esophagus: an overlooked cause of chest pain as a complication of esophageal foreign bodies.Journal of Zhejiang University. Science. B · 2023Article
- Index of microcirculatory resistance: state-of-the-art and potential applications in computational simulation of coronary artery disease.Journal of Zhejiang University. Science. B · 2022Article
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10 authors.
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Abstract
objectivesThis study evaluated the prognostic power of serum uric acid (UA) in predicting adverse events in elderly acute coronary syndrome (ACS) patients with diabetes mellitus (DM).
methodsThe analysis involved 718 ACS patients >80 years old whose general clinical data and baseline blood biochemical indicators were collected prospectively from January 2006 to December 2012. These patients were classified into two groups based on DM status, and then followed up after discharge. The Kaplan-Meier method was used for major adverse cardiac event (MACE) rates and all-cause mortality. Multivariate Cox regression was performed to analyze the relationship between UA level and long-term clinical prognosis. Receiver operating characteristic (ROC) curves were analyzed to predict the cutoff value of UA in elderly ACS patients with DM. There were 242 and 476 patients in the DM and non-DM (NDM) groups, respectively, and the follow-up time after discharge was 40‒120 months (median, 63 months; interquartile range, 51‒74 months).
resultsThe all-cause mortality, cardiac mortality, and MACE rates in both DM and NDM patients were higher than those in the control group (
conclusionsSerum UA level is a strong independent predictor of long-term all-cause death and MACE in elderly ACS patients with DM.
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