Evidence map›Paper›PMID 34638732›Full record

Trial reportInternational journal of molecular sciences2021

Relationships between Mitochondrial Function, AMPK, and TORC1 Signaling in Lymphoblasts with Premutation Alleles of the FMR1 Gene.

Paul R Fisher, Claire Y Allan, Oana Sanislav, Anna Atkinson, Kevin R W Ngoei, Bruce E Kemp, Elsdon Storey, Danuta Z Loesch, Sarah J Annesley

Open access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Paul R FisherDepartment of Physiology Anatomy and Microbiology, La Trobe University, Bundoora, VIC 3086, Australia.ORCID 0000-0003-1884-6306
Claire Y AllanDepartment of Physiology Anatomy and Microbiology, La Trobe University, Bundoora, VIC 3086, Australia.
Oana SanislavDepartment of Physiology Anatomy and Microbiology, La Trobe University, Bundoora, VIC 3086, Australia.
Anna AtkinsonSchool of Psychology and Public Health, La Trobe University, Bundoora, VIC 3086, Australia.
Kevin R W NgoeiSt. Vincent's Institute of Medical Research, Department of Medicine, University of Melbourne, Fitzroy, VIC 3065, Australia.
Bruce E KempSt. Vincent's Institute of Medical Research, Department of Medicine, University of Melbourne, Fitzroy, VIC 3065, Australia.
Elsdon StoreyDepartment of Medicine, Alfred Hospital Campus, Monash University, Commercial Road, Melbourne, VIC 3004, Australia.
Danuta Z LoeschSchool of Psychology and Public Health, La Trobe University, Bundoora, VIC 3086, Australia.
Sarah J AnnesleyDepartment of Physiology Anatomy and Microbiology, La Trobe University, Bundoora, VIC 3086, Australia.ORCID 0000-0002-7604-3985
La Trobe University · AUThe University of Melbourne · AUMonash University · AU

Funding

Michael J Fox and Shake It Up Australia Foundations 10862National Health and Medical Research Australia CF06/0269National Institutes of Child Health and Human Development 36071
6 · The paper itself

Abstract

The X-linked

Indexed as

AllelesAMP-Activated Protein KinasesFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeMechanistic Target of Rapamycin Complex 1MitochondriaMitochondrial ProteinsTrinucleotide Repeat ExpansionFemaleHumansLymphocytesMaleSignal TransductionAMP-Activated Protein KinasesFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1Mechanistic Target of Rapamycin Complex 1Mitochondrial ProteinsAMPKCGG repeatFMR1fragile X-associated tremor/ataxia syndrome (FXTAS)mitochondriaTOR complex I

Identifiers

PMID34638732
PMCPMC8508849
OpenAlexW3204089932

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.