Evidence map›Paper›PMID 34639187›Full record

ArticleInternational journal of molecular sciences2021

Novel DNA Aptameric Sensors to Detect the Toxic Insecticide Fenitrothion.

Kien Hong Trinh, Ulhas Sopanrao Kadam, Jinnan Song, Yuhan Cho, Chang Ho Kang, Kyun Oh Lee, Chae Oh Lim, Woo Sik Chung, Jong Chan Hong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 3 countries.

Kien Hong TrinhDivision of Life Science and Applied Life Science, Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Ulhas Sopanrao KadamDivision of Life Science and Applied Life Science, Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Jinnan SongDivision of Life Science and Applied Life Science, Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.ORCID 0000-0002-8821-2678
Yuhan ChoDivision of Life Science and Applied Life Science, Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Chang Ho KangDivision of Life Science and Applied Life Science, Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.ORCID 0000-0003-4342-5247
Kyun Oh LeeDivision of Life Science and Applied Life Science, Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Chae Oh LimDivision of Life Science and Applied Life Science, Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Woo Sik ChungDivision of Life Science and Applied Life Science, Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Jong Chan HongDivision of Life Science and Applied Life Science, Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Gyeongsang National University · KR

Funding

BK21 ProgramNational Research Foundation of Korea 2020R1A1A03044344Rural Development Administration PJ01623501
6 · The paper itself

Abstract

Fenitrothion is an insecticide belonging to the organophosphate family of pesticides that is widely used around the world in agriculture and living environments. Today, it is one of the most hazardous chemicals that causes severe environmental pollution. However, detection of fenitrothion residues in the environment is considered a significant challenge due to the small molecule nature of the insecticide and lack of molecular recognition elements that can detect it with high specificity. We performed in vitro selection experiments using the SELEX process to isolate the DNA aptamers that can bind to fenitrothion. We found that newly discovered DNA aptamers have a strong ability to distinguish fenitrothion from other organophosphate insecticides (non-specific targets). Furthermore, we identified a fenitrothion-specific aptamer; FenA2, that can interact with Thioflavin T (ThT) to produce a label-free detection mode with a

Indexed as

Aptamers, NucleotideBiosensing TechniquesBrassicaFenitrothionInsecticidesPlant ExtractsSELEX Aptamer TechniqueAptamers, NucleotideFenitrothionInsecticidesPlant ExtractsaptamerfenitrothionfluorescenceinsecticideSELEXthioflavin T

Identifiers

PMID34639187
PMCPMC8509669
OpenAlexW3205999254

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.