Evidence map›Paper›PMID 34641434›Full record

ReviewMolecules (Basel, Switzerland)2021

Effects of Wine Components in Inflammatory Bowel Diseases.

Josip Vrdoljak, Marko Kumric, Tina Ticinovic Kurir, Ivan Males, Dinko Martinovic, Marino Vilovic, Josko Bozic

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Josip VrdoljakDepartment of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.
Marko KumricDepartment of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0002-9696-3359
Tina Ticinovic KurirDepartment of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.
Ivan MalesDepartment of Surgery, University Hospital of Split, 21000 Split, Croatia.
Dinko MartinovicDepartment of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0003-2060-5130
Marino VilovicDepartment of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0002-5433-5063
Josko BozicDepartment of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0003-1634-0635
University of Split · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the rising prevalence of Inflammatory bowel disease (IBD) worldwide, and the rising cost of treatment with novel biological drugs, there is an increasing interest in various diets and natural foods as a potential way to control/modulate IBD. As recent data indicates that diet can modify the metabolic responses essential for the resolution of inflammation, and as wine compounds have been shown to provide substantial anti-inflammatory effect, in this review we aimed to discuss the current evidence concerning the impact of biological compounds present in wine on IBD. A number of preclinical studies brought forth strong evidence on the mechanisms by which molecules in wine, such as resveratrol or piceatannol, provide their anti-inflammatory, anti-oxidative, anti-tumor, and microbiota-modulation effects. However, concerning the effects of alcohol, it is still unclear how the amount of ethanol ingested within the framework of moderate wine consumption (1-2 glasses a day) affects patients with IBD, as human studies regarding the effects of wine on patients with IBD are scarce. Nevertheless, available evidence justifies the conductance of large-scale RCT trials on human subjects that will finally elucidate whether wine can offer real benefits to the IBD population.

Indexed as

AnimalsAnti-Inflammatory AgentsHumansInflammatory Bowel DiseasesWineAnti-Inflammatory AgentsCrohn’s diseasedietinflammationinflammatory bowel diseasepolyphenolsresveratrolulcerative colitiswine

Identifiers

PMID34641434
PMCPMC8512001
OpenAlexW3204014861

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.