Evidence map›Paper›PMID 34641920›Full record

ReviewJournal of nanobiotechnology2021

Nanofiber-based systems intended for diabetes.

Hassan Maleki, Kamyar Khoshnevisan, Sayed Mahmoud Sajjadi-Jazi, Hadi Baharifar, Maryam Doostan, Nazanin Khoshnevisan, Farshad Sharifi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
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  12. Heliyon · 2024
    Article
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  16. Article
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  19. Review
  20. Nanobiotechnology: Applications in Chronic Wound Healing.International journal of nanomedicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Hassan Maleki *Nano Drug Delivery Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran. Hasan.maleki@kums.ac.ir.
Kamyar Khoshnevisan *Medical Nanotechnology and Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. kamyar.khoshnevisan@gmail.com.ORCID http://orcid.org/0000-0003-1250-4292
Sayed Mahmoud Sajjadi-JaziCell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, 1411713137, Tehran, Iran.
Hadi BaharifarDepartment of Medical Nanotechnology, Applied Biophotonics Research Center, Science and Research Branch, Islamic Azad University, 1477893855, Tehran, Iran.
Maryam DoostanNano Drug Delivery Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Nazanin KhoshnevisanResearch and Development Team, Evolution Wound Dressing (EWD) Startup Co., Tehran, Iran.
Farshad SharifiResearch and Development Team, Evolution Wound Dressing (EWD) Startup Co., Tehran, Iran.
Kermanshah University of Medical Sciences · IRIran University of Medical Sciences · IRIslamic Azad University, Science and Research Branch · IRKhayyam University · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic mellitus (DM) is the most communal metabolic disease resulting from a defect in insulin secretion, causing hyperglycemia by promoting the progressive destruction of pancreatic β cells. This autoimmune disease causes many severe disorders leading to organ failure, lower extremity amputations, and ultimately death. Modern delivery systems e.g., nanofiber (NF)-based systems fabricated by natural and synthetic or both materials to deliver therapeutics agents and cells, could be the harbinger of a new era to obviate DM complications. Such delivery systems can effectively deliver macromolecules (insulin) and small molecules. Besides, NF scaffolds can provide an ideal microenvironment to cell therapy for pancreatic β cell transplantation and pancreatic tissue engineering. Numerous studies indicated the potential usage of therapeutics/cells-incorporated NF mats to proliferate/regenerate/remodeling the structural and functional properties of diabetic skin ulcers. Thus, we intended to discuss the aforementioned features of the NF system for DM complications in detail.

Indexed as

Drug Delivery SystemsNanofibersTissue EngineeringAnimalsBandagesCell Line, TumorDiabetes MellitusDiabetic FootHumansInsulin-Secreting CellsMiceRatsCell transplantationDelivery systemsDiabetic woundElectrospinningNanofiberScaffoldWound dressing

Identifiers

PMID34641920
PMCPMC8513238
OpenAlexW3206036069

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.