Evidence map›Paper›PMID 34644511›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Matrix Metalloproteinase-8 in Pulmonary Hypertension: The Sheep in the Wolf's Skin?

Elena A Goncharova, Tatiana V Kudryashova, Giovanni Maroli, Soni S Pullamsetti

Open access · hybridAbstract readEditorialComment
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Pulmonary Hypertension: A Contemporary Review.American journal of respiratory and critical care medicine · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Elena A GoncharovaDepartment of Internal Medicine University of California, Davis Davis, California.ORCID 0000-0001-7118-6752
Tatiana V KudryashovaDepartment of Internal Medicine University of California, Davis Davis, California.
Giovanni MaroliDepartment of Lung Development and Remodeling Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL) Bad Nauheim, Germany.
Soni S PullamsettiDepartment of Lung Development and Remodeling Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL) Bad Nauheim, Germany.ORCID 0000-0003-0440-8831
Max Planck Institute for Heart and Lung Research · DEUniversity of California System · US

Funding

HIPPO Signaling in Pulmonary Arterial HypertensionR01HL130261 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GONCHAROVA, ELENA · 2016 to 2023
$3.5M
TSC2 Signaling in Pulmonary Arterial HypertensionR01HL113178 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GONCHAROVA, ELENA · 2012 to 2021
$3.1M
NHLBI NIH HHS R01 HL113178NHLBI NIH HHS R01 HL130261
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hypertension, PulmonaryWolvesAnimalsMatrix Metalloproteinase 8SheepMatrix Metalloproteinase 8

Identifiers

PMID34644511
PMCPMC8865723
OpenAlexW3207645520

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.