Evidence map›Paper›PMID 34644679›Full record

ArticleBiomedical physics & engineering express2021

Faster super-resolution ultrasound imaging with a deep learning model for tissue decluttering and contrast agent localization.

Katherine G Brown, Scott Chase Waggener, Arthur David Redfern, Kenneth Hoyt

Abstract read
In one paragraph

Article in Biomedical physics & engineering express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Advancements in Three-Dimensional Super-Resolution Ultrasound Imaging: A Narrative Review.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
    Review
  4. Article
  5. Current trends in the characterization and monitoring of vascular response to cancer therapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. 3-D Super-Resolution Ultrasound Imaging for Monitoring Early Changes in Breast Cancer after Treatment with a Vascular-Disrupting Agent.IEEE International Ultrasonics Symposium : [proceedings]. IEEE International Ultrasonics Symposium · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katherine G BrownDepartment of Bioengineering, University of Texas at Dallas, Richardson, TX, United States of America.ORCID 0000-0003-2790-538X
Scott Chase WaggenerMedCognetics, Dallas, TX, United States of America.
Arthur David RedfernDepartment of Computer Science, University of Texas at Dallas, Richardson, TX, United States of America.
Kenneth HoytDepartment of Bioengineering, University of Texas at Dallas, Richardson, TX, United States of America.ORCID 0000-0003-2379-8273

Funding

Multiparametric ultrasound imaging for early detection of nonalcoholic fatty liver diseaseR01DK126833 · NIDDK · UNIVERSITY OF TEXAS DALLAS · PI HOYT, KENNETH · 2021 to 2024
$1.6M
3D Super-Resolution Ultrasound Imaging for Cancer Detection and Treatment MonitoringR01EB025841 · NIBIB · UNIVERSITY OF TEXAS DALLAS · PI HOYT, KENNETH · 2019 to 2022
$1.3M
NIBIB NIH HHS R01 EB025841NIDDK NIH HHS R01 DK126833
6 · The paper itself

Abstract

Super-resolution ultrasound (SR-US) imaging allows visualization of microvascular structures as small as tens of micrometers in diameter. However, use in the clinical setting has been impeded in part by ultrasound (US) acquisition times exceeding a breath-hold and by the need for extensive offline computation. Deep learning techniques have been shown to be effective in modeling the two more computationally intensive steps of microbubble (MB) contrast agent detection and localization. Performance gains by deep networks over conventional methods are more than two orders of magnitude and in addition the networks can localize overlapping MBs. The ability to separate overlapping MBs allows use of higher contrast agent concentrations and reduces US image acquisition time. Herein we propose a fully convolutional neural network (CNN) architecture to perform the operations of MB detection as well as localization in a single model. Termed SRUSnet, the network is based on the MobileNetV3 architecture modified for 3-D input data, minimal convergence time, and high-resolution data output using a flexible regression head. Also, we propose to combine linear B-mode US imaging and nonlinear contrast pulse sequencing (CPS) which has been shown to increase MB detection and further reduce the US image acquisition time. The network was trained with

Indexed as

Deep LearningAnimalsContrast MediaMicrobubblesPhantoms, ImagingRatsUltrasonographyContrast Mediacontrast-enhanced ultrasounddeep learningmicrobubblesplane-wavessuper-resolution ultrasound

Identifiers

PMID34644679
PMCPMC8594285

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.