Evidence map›Paper›PMID 34646237›Full record

GuidelineFrontiers in endocrinology2021

Guidelines for Biobanking of Bone Marrow Adipose Tissue and Related Cell Types: Report of the Biobanking Working Group of the International Bone Marrow Adiposity Society.

Stephanie Lucas, Michaela Tencerova, Benoit von der Weid, Thomas Levin Andersen, Camille Attané, Friederike Behler-Janbeck, William P Cawthorn, Kaisa K Ivaska, Olaia Naveiras, Izabela Podgorski and 2 more

Open access · goldAbstract readGuidelineReview
In one paragraph

Guideline in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 12 institutions in 9 countries.

Stephanie LucasMarrow Adiposity and Bone Lab-MABLab ULR4490, Univ. Littoral Côte d'Opale, Boulogne-sur-Mer, Univ. Lille, CHU Lille, Lille, France.
Michaela TencerovaMolecular Physiology of Bone, Institute of Physiology of the Czech Academy of Sciences, Prague, Czechia.
Benoit von der WeidSchool of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Thomas Levin AndersenClinical Cell Biology, Department of Pathology, Odense University Hospital, Odense, Denmark.
Camille AttanéInstitute of Pharmacology and Structural Biology, Université de Toulouse, CNRS UMR 5089, Toulouse, France.
Friederike Behler-JanbeckDepartment of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
William P CawthornBritish Heart Foundation Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Kaisa K IvaskaInstitute of Biomedicine, University of Turku, Turku, Finland.
Olaia NaveirasDepartment of Biomedical Sciences, Faculty of Biology and Medicine, Université de Lausanne, Lausanne, Switzerland.
Izabela PodgorskiDepartment of Pharmacology, Wayne State University School of Medicine and Karmanos Cancer Institute, Detroit, MI, United States.
Michaela R ReaganCenter for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME, United States.
Bram C J van der EerdenLaboratory for Calcium and Bone Metabolism, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands.
Adiposité Médullaire et OsCzech Academy of Sciences, Institute of Physiology · CZErasmus MC · NLLa Ligue Contre le Cancer · FRMaine Medical Center · USSIB Swiss Institute of Bioinformatics · CHUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Edinburgh · GBUniversity of Lausanne · CHUniversity of Southern Denmark · DKUniversity of Turku · FIWayne State University · US

Funding

Understanding Factors Influencing COVID-19 Testing and Vaccination in Immigrant Low-income and Homeless Populations and Testing Targeted InterventionsU54GM115516 · NIGMS · MAINEHEALTH · PI Susan L SANTANGELO · 2017 to 2026
$51.6M
The role of night shift work in metabolic disorders during and after pregnancyP20GM121301 · NIGMS · MAINEHEALTH · PI CLIFFORD JAMES ROSEN · 2017 to 2026
$25.1M
Defining the Roles of Bone Marrow Adipocytes and FABP4/5 Signaling in Multiple Myeloma Drug Resistance - Diversity SupplementR37CA245330 · NCI · MAINEHEALTH · PI REAGAN, MICHAELA R. · 2020 to 2025
$2.8M
Adipocyte regulation of tumor survival in metastatic prostate cancer: new targets for therapyR01CA251394 · NCI · WAYNE STATE UNIVERSITY · PI PODGORSKI, IZABELA · 2020 to 2024
$2.0M
Functional Role of Bone Marrow Adipocytes in Metastatic Prostate CancerR01CA181189 · NCI · WAYNE STATE UNIVERSITY · PI PODGORSKI, IZABELA · 2014 to 2018
$1.6M
Medical Research Council MR/M021394/1Medical Research Council MR/S010505/1NCI NIH HHS R01 CA181189NCI NIH HHS R01 CA251394NCI NIH HHS R37 CA245330NIGMS NIH HHS P20 GM121301
6 · The paper itself

Abstract

Over the last two decades, increased interest of scientists to study bone marrow adiposity (BMA) in relation to bone and adipose tissue physiology has expanded the number of publications using different sources of bone marrow adipose tissue (BMAT). However, each source of BMAT has its limitations in the number of downstream analyses for which it can be used. Based on this increased scientific demand, the International Bone Marrow Adiposity Society (BMAS) established a Biobanking Working Group to identify the challenges of biobanking for human BMA-related samples and to develop guidelines to advance establishment of biobanks for BMA research. BMA is a young, growing field with increased interest among many diverse scientific communities. These bring new perspectives and important biological questions on how to improve and build an international community with biobank databases that can be used and shared all over the world. However, to create internationally accessible biobanks, several practical and legislative issues must be addressed to create a general ethical protocol used in all institutes, to allow for exchange of biological material internationally. In this position paper, the BMAS Biobanking Working Group describes similarities and differences of patient information (PIF) and consent forms from different institutes and addresses a possibility to create uniform documents for BMA biobanking purposes. Further, based on discussion among Working Group members, we report an overview of the current isolation protocols for human bone marrow adipocytes (BMAds) and bone marrow stromal cells (BMSCs, formerly mesenchymal), highlighting the specific points crucial for effective isolation. Although we remain far from a unified BMAd isolation protocol and PIF, we have summarized all of these important aspects, which are needed to build a BMA biobank. In conclusion, we believe that harmonizing isolation protocols and PIF globally will help to build international collaborations and improve the quality and interpretation of BMA research outcomes.

Indexed as

Adipose TissueBone MarrowAdiposityBiological Specimen BanksHumansTissue Banksbiobankingbone marrow adipocytesbone marrow adipositybone marrow stromal cellscell isolation protocolsclinical studiesinternational research networkspatient information

Identifiers

PMID34646237
PMCPMC8503265
OpenAlexW3204682710

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.