Evidence map›Paper›PMID 34646608›Full record

ArticleCureus2021

Raynaud's Secondary to Granulomatosis With Polyangiitis.

Sai Swarupa Vulasala, Shohana Ahmed, Nirmal K Onteddu, Maneesh Mannem, Srikanth Mukkera

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sai Swarupa VulasalaRadiology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Shohana AhmedInternal Medicine, Texas Tech University Health Sciences Center - Permian Basin, Odessa, USA.
Nirmal K OntedduInternal Medicine, Flowers Hospital, Dothan, USA.
Maneesh MannemInternal Medicine, Texas Tech University Health Sciences Center - Permian Basin, Odessa, USA.
Srikanth MukkeraDivision of Rheumatology, Texas Tech University Health Sciences Center, Odessa, USA.
Florida College · USTexas Tech University Health Sciences Center · USFlower Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Raynaud's phenomenon (RP) is an episodic digital vasospastic condition that is prevalent among 5% of the population. The symptoms range from reversible pallor to ischemia and gangrene. RP can be primary or secondary. We discuss a case of severe RP secondary to granulomatosis with polyangiitis (GPA) that presented with ischemia and gangrene. Studies show that approximately <1% of GPA cases have similar presentations. Early diagnosis and management are essential to halt the progression of ischemia. Calcium channel blockers are the first-line medications used in RP. Phosphodiesterase type 5 inhibitors, endothelin receptor antagonists, and prostacyclin analogs are proven to be effective in cases of severe RP. Sympathectomy and amputation are considered as the extreme options in patients with refractory symptoms.

Indexed as

bosentancalcium channel blockersemerging therapiesgranulomatosis with polyangiitisprostacyclinsraynaud phenomenonrefractory raynaudssecondary raynaudsildenafilwegener granulomatosis

Identifiers

PMID34646608
PMCPMC8481133
OpenAlexW3196798035

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.