Evidence map›Paper›PMID 34649938›Full record

ArticleLife science alliance2021

A brain-specific

Oswaldo A Lozoya, Fuhua Xu, Dagoberto Grenet, Tianyuan Wang, Korey D Stevanovic, Jesse D Cushman, Thomas B Hagler, Artiom Gruzdev, Patricia Jensen, Bairon Hernandez and 4 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Life science alliance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Glucocorticoid Receptor Translational Isoforms Generate Unique Glucocorticoid Responses in the Mouse Brain.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Oswaldo A LozoyaGenomic Integrity and Structural Biology Laboratory, National Institutes of Health, Durham, NC, USA.
Fuhua XuGenomic Integrity and Structural Biology Laboratory, National Institutes of Health, Durham, NC, USA.
Dagoberto GrenetGenomic Integrity and Structural Biology Laboratory, National Institutes of Health, Durham, NC, USA.
Tianyuan WangIntegrative Bioinformatics Branch, National Institutes of Health, Durham, NC, USA.
Korey D StevanovicNeurobehavioral Core Laboratory, National Institutes of Health, Durham, NC, USA.ORCID 0000-0003-4453-1631
Jesse D CushmanNeurobehavioral Core Laboratory, National Institutes of Health, Durham, NC, USA.
Thomas B HaglerKnockout Mouse Core Facility, National Institutes of Health, Durham, NC, USA.
Artiom GruzdevKnockout Mouse Core Facility, National Institutes of Health, Durham, NC, USA.ORCID 0000-0002-1698-7159
Patricia JensenNeurobiology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA.
Bairon HernandezCentro de Bioinformática y Simulación Molecular, Facultad de Ingeniería, Universidad de Talca, Talca, Chile.
Gonzalo RiadiCentro de Bioinformática y Simulación Molecular, Facultad de Ingeniería, Universidad de Talca, Talca, Chile.
Sheryl S MoyDepartment of Psychiatry, Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Janine H SantosGenomic Integrity and Structural Biology Laboratory, National Institutes of Health, Durham, NC, USA janine.santos@nih.gov.ORCID 0000-0001-6384-3070
Richard P WoychikGenomic Integrity and Structural Biology Laboratory, National Institutes of Health, Durham, NC, USA rick.woychik@nih.gov.ORCID 0000-0001-8196-1732
National Institutes of Health · USUniversity of Talca · CLUniversity of North Carolina at Chapel Hill · US

Funding

Preclinical CoreP50HD103573 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GABRIEL S DICHTER · 2020 to 2026
$9.7M
Preclinical CoreU54HD079124 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BELGER, AYSENIL · 2013 to 2019
$8.0M
NICHD NIH HHS P50 HD103573NICHD NIH HHS U54 HD079124
6 · The paper itself

Abstract

PGC1α is a transcriptional coactivator in peripheral tissues, but its function in the brain remains poorly understood. Various brain-specific

Indexed as

Behavior, AnimalGene ExpressionAnimalsCerebellumElevated Plus Maze TestFemaleLocomotionMaleMiceMice, Inbred C57BLMice, TransgenicMotor ActivityMutationNeuronsOpen Field TestPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, mouseProtein Isoforms

Identifiers

PMID34649938
PMCPMC8548212
OpenAlexW3204981800

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.