Evidence map›Paper›PMID 34650191›Full record

ArticleNPJ digital medicine2021

Walking on common ground: a cross-disciplinary scoping review on the clinical utility of digital mobility outcomes.

Ashley Polhemus, Laura Delgado-Ortiz, Gavin Brittain, Nikolaos Chynkiamis, Francesca Salis, Heiko Gaßner, Michaela Gross, Cameron Kirk, Rachele Rossanigo, Kristin Taraldsen and 39 more

Open access · goldAbstract readScoping Review
In one paragraph

Article in NPJ digital medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 4 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 4 syntheses or guidelines pooled it, 103 citations in OpenAlex.

  1. Pooled it
  2. Gait differences between COPD and healthy controls: systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Observational
  9. Article
  10. Walking as a Window to the Brain: Redefining Gait in Neurology.Medical sciences (Basel, Switzerland) · 2026
    Review
  11. Qualitative assessment of mobility in older adults: a scoping review of process-oriented behavioural criteria.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Review
  12. Observational
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Digital assessment of real-world walking in people with impaired mobility: How many hours and days are needed?The international journal of behavioral nutrition and physical activity · 2025
    Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors at 17 institutions in 8 countries.

Ashley PolhemusEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland. ashley.polhemus@uzh.ch.ORCID http://orcid.org/0000-0002-5056-5785
Laura Delgado-OrtizISGlobal, Barcelona, Spain.ORCID http://orcid.org/0000-0003-0311-7661
Gavin BrittainDepartment of Neuroscience and Sheffield NIHR Translational Neuroscience BRC, Sheffield Teaching Hospitals NHS Foundation Trust & University of Sheffield, Sheffield, England.ORCID http://orcid.org/0000-0002-9903-7203
Nikolaos ChynkiamisDepartment of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University Newcastle, Newcastle, UK.ORCID http://orcid.org/0000-0002-9595-6974
Francesca SalisDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Heiko GaßnerDepartment of Molecular Neurology, University Hospital Erlangen, Erlangen, Germany.ORCID http://orcid.org/0000-0003-2037-9460
Michaela GrossDepartment of Clinical Gerontology, Robert-Bosch-Hospital, Stuttgart, Germany.
Cameron KirkTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Rachele RossanigoDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Kristin TaraldsenDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.
Diletta BaltaDepartment of Electronics and Telecommunications, Politecnico di Torino, Torino, Italy.
Sofie BreulsDepartment of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-6474-6923
Sara ButteryNational Heart and Lung Institute, Imperial College London, London, UK.
Gabriela CardenasISGlobal, Barcelona, Spain.
Christoph EndressDepartment of Clinical Gerontology, Robert-Bosch-Hospital, Stuttgart, Germany.
Julia GugenhanDepartment of Clinical Gerontology, Robert-Bosch-Hospital, Stuttgart, Germany.
Alison KeoghInsight Centre for Data Analytics, University College Dublin, Dublin, Ireland.
Felix KlugeDepartment of Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.ORCID http://orcid.org/0000-0003-4921-6104
Sarah KochISGlobal, Barcelona, Spain.
M Encarna Micó-AmigoTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Corinna NerzDepartment of Clinical Gerontology, Robert-Bosch-Hospital, Stuttgart, Germany.ORCID http://orcid.org/0000-0001-5160-796X
Chloé SieberEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-6642-5082
Parris WilliamsNational Heart and Lung Institute, Imperial College London, London, UK.
Ronny BergquistDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.
Magda Bosch de BaseaISGlobal, Barcelona, Spain.
Ellen BuckleyInsigneo Institute, Department of Mechanical Engineering, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0002-0968-6286
Clint HansenDepartment of Neurology, University Medical Center Schleswig-Holstein, Kiel, Germany.ORCID http://orcid.org/0000-0003-4813-3868
A Stefanie MikolaizakDepartment of Clinical Gerontology, Robert-Bosch-Hospital, Stuttgart, Germany.
Lars SchwickertDepartment of Clinical Gerontology, Robert-Bosch-Hospital, Stuttgart, Germany.
Kirsty ScottInsigneo Institute, Department of Mechanical Engineering, University of Sheffield, Sheffield, UK.
Sabine StallforthDepartment of Molecular Neurology, University Hospital Erlangen, Erlangen, Germany.
Janet van UemDepartment of Neurology, University Medical Center Schleswig-Holstein, Kiel, Germany.
Beatrix VereijkenDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.ORCID http://orcid.org/0000-0002-2231-8138
Andrea CereattiDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Heleen DemeyerDepartment of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.
Nicholas HopkinsonNational Heart and Lung Institute, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-3235-0454
Walter MaetzlerDepartment of Neurology, University Medical Center Schleswig-Holstein, Kiel, Germany.ORCID http://orcid.org/0000-0002-5945-4694
Thierry TroostersDepartment of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.
Ioannis VogiatzisDepartment of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University Newcastle, Newcastle, UK.
Alison YarnallTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Clemens BeckerDepartment of Clinical Gerontology, Robert-Bosch-Hospital, Stuttgart, Germany.
Judith Garcia-AymerichISGlobal, Barcelona, Spain.ORCID http://orcid.org/0000-0002-7097-4586
Letizia LeocaniDepartment of Neurology, San Raffaele University, Milan, Italy.
Claudia MazzàInsigneo Institute, Department of Mechanical Engineering, University of Sheffield, Sheffield, UK.
Lynn RochesterTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Basil SharrackDepartment of Neuroscience and Sheffield NIHR Translational Neuroscience BRC, Sheffield Teaching Hospitals NHS Foundation Trust & University of Sheffield, Sheffield, England.
Anja FreiEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Milo PuhanEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Mobilise-D
Robert Bosch Hospital · DEUniversitat Pompeu Fabra · ESNewcastle University · GBUniversity of Zurich · CHImperial College London · GBInsigneo · GBNorwegian University of Science and Technology · NOUniversity of Sassari · ITKU Leuven · BENorthumbria University · GBSheffield Teaching Hospitals NHS Foundation Trust · GBUniversitätsklinikum Erlangen · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEGhent University Hospital · BEPolitecnico di Torino · ITSan Raffaele University of Rome · ITUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical mobility is essential to health, and patients often rate it as a high-priority clinical outcome. Digital mobility outcomes (DMOs), such as real-world gait speed or step count, show promise as clinical measures in many medical conditions. However, current research is nascent and fragmented by discipline. This scoping review maps existing evidence on the clinical utility of DMOs, identifying commonalities across traditional disciplinary divides. In November 2019, 11 databases were searched for records investigating the validity and responsiveness of 34 DMOs in four diverse medical conditions (Parkinson's disease, multiple sclerosis, chronic obstructive pulmonary disease, hip fracture). Searches yielded 19,672 unique records. After screening, 855 records representing 775 studies were included and charted in systematic maps. Studies frequently investigated gait speed (70.4% of studies), step length (30.7%), cadence (21.4%), and daily step count (20.7%). They studied differences between healthy and pathological gait (36.4%), associations between DMOs and clinical measures (48.8%) or outcomes (4.3%), and responsiveness to interventions (26.8%). Gait speed, step length, cadence, step time and step count exhibited consistent evidence of validity and responsiveness in multiple conditions, although the evidence was inconsistent or lacking for other DMOs. If DMOs are to be adopted as mainstream tools, further work is needed to establish their predictive validity, responsiveness, and ecological validity. Cross-disciplinary efforts to align methodology and validate DMOs may facilitate their adoption into clinical practice.

Identifiers

PMID34650191
PMCPMC8516969
OpenAlexW3206132326

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.