Evidence map›Paper›PMID 34650596›Full record

ArticleFrontiers in genetics2021

Peopling History of the Tibetan Plateau and Multiple Waves of Admixture of Tibetans Inferred From Both Ancient and Modern Genome-Wide Data.

Guanglin He, Mengge Wang, Xing Zou, Pengyu Chen, Zheng Wang, Yan Liu, Hongbin Yao, Lan-Hai Wei, Renkuan Tang, Chuan-Chao Wang and 1 more

Abstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  3. Genetic structure and admixture of the Yi and Qiang in southwestern China.Journal of Zhejiang University. Science. B · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Guanglin HeSchool of Humanities, Nanyang Technological University, Singapore, Singapore.
Mengge WangInstitute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, China.
Xing ZouInstitute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, China.
Pengyu ChenCenter of Forensic Expertise, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zheng WangInstitute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, China.
Yan LiuSchool of Basic Medical Sciences, North Sichuan Medical College, Nanchong, China.
Hongbin YaoKey Laboratory of Evidence Science of Gansu Province, Gansu Institute of Political Science and Law, Lanzhou, China.
Lan-Hai WeiDepartment of Anthropology and Ethnology, Institute of Anthropology, School of Sociology and Anthropology, Xiamen University, Xiamen, China.
Renkuan TangDepartment of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, China.
Chuan-Chao WangState Key Laboratory of Cellular Stress Biology, National Institute for Data Science in Health and Medicine, School of Life Sciences, Xiamen University, Xiamen, China.
Hui-Yuan YehSchool of Humanities, Nanyang Technological University, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Archeologically attested human occupation on the Tibetan Plateau (TP) can be traced back to 160 thousand years ago (kya) via the archaic Xiahe people and 30∼40 kya via the Nwya Devu anatomically modern human. However, the history of the Tibetan populations and their migration inferred from the ancient and modern DNA remains unclear. Here, we performed the first ancient and modern genomic meta-analysis among 3,017 Paleolithic to present-day Eastern Eurasian genomes (2,444 modern individuals from 183 populations and 573 ancient individuals). We identified a close genetic connection between the ancient-modern highland Tibetans and lowland island/coastal Neolithic Northern East Asians (NEA). This observed genetic affinity reflected the primary ancestry of high-altitude Tibeto-Burman speakers originated from the Neolithic farming populations in the Yellow River Basin. The identified pattern was consistent with the proposed common north-China origin hypothesis of the Sino-Tibetan languages and dispersal patterns of the northern millet farmers. We also observed the genetic differentiation between the highlanders and lowland NEAs. The former harbored more deeply diverged Hoabinhian/Onge-related ancestry and the latter possessed more Neolithic southern East Asian (SEA) or Siberian-related ancestry. Our reconstructed

Indexed as

ancient genomesEast Asiangenetic historySino-TibetanTibetan Plateau

Identifiers

PMID34650596
PMCPMC8506211

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.