Influence of epidural anesthesia and general anesthesia on thromboembolism in patients undergoing total knee arthroplasty.

Dongzhi Liu, Chengliang Sun, Xiuli Zhang, Zhibin Zhao

Open access · greenAbstract read

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Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

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4citing papers in PubMed

1.3field-weighted citation impact, top 18% of its field

1 · What the graph read from it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

Risk of deep vein thrombosis (DVT) in lower extremity after total knee arthroplasty (TKA) in patients over 60 years old.Journal of orthopaedic surgery and research · 2023
Article
Effect of Thoracic Paravertebral Nerve Block on Blood Coagulation in Patients After Thoracoscopic Lobectomy: A Prospective Randomized Controlled Clinical Trial.Journal of pain research · 2022
Article
Effects of general anesthesia and epidural anesthesia on deep vein thrombosis and perioperative cognitive function of patients undergoing total knee arthroplasty.American journal of translational research · 2022
Article
Epidural Anesthesia versus General Anesthesia for Total Knee Arthroplasty: Influences on Perioperative Cognitive Function and Deep Vein Thrombosis.Computational and mathematical methods in medicine · 2022
Article

4 · The record

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5 · Who and what money

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4 authors at 1 institution in 1 country.

Dongzhi LiuDepartment of Anesthesiology, The First People's Hospital of Lianyungang, The Affiliated Lianyungang Hospital of Xuzhou Medical University, The First Affiliated Hospital of Kangda College of Nanjing Medical University, Lianyungang Clinical College of Nanjing Medical University Lianyungang 222000, Jiangsu Province, China.

Chengliang SunDepartment of Anesthesiology, The First People's Hospital of Lianyungang, The Affiliated Lianyungang Hospital of Xuzhou Medical University, The First Affiliated Hospital of Kangda College of Nanjing Medical University, Lianyungang Clinical College of Nanjing Medical University Lianyungang 222000, Jiangsu Province, China.

Xiuli ZhangDepartment of Anesthesiology, The First People's Hospital of Lianyungang, The Affiliated Lianyungang Hospital of Xuzhou Medical University, The First Affiliated Hospital of Kangda College of Nanjing Medical University, Lianyungang Clinical College of Nanjing Medical University Lianyungang 222000, Jiangsu Province, China.

Zhibin ZhaoDepartment of Anesthesiology, The First People's Hospital of Lianyungang, The Affiliated Lianyungang Hospital of Xuzhou Medical University, The First Affiliated Hospital of Kangda College of Nanjing Medical University, Lianyungang Clinical College of Nanjing Medical University Lianyungang 222000, Jiangsu Province, China.

Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to explore the application value of epidural and general anesthesia in total knee arthroplasty (TKA).

methodsWe first retrospectively analyzed 156 patients who underwent total knee arthroplasty in our hospital from January 2019 to January 2020 as subjects. The control group (CG) included 86 subject who were treated with general anesthesia. The remaining 70 subjects with epidural anesthesia were divided to a research group (RG). The recovery and adverse reactions after surgery were compared. The coagulation function before and after surgery was analyzed. The incidence of deep vein thrombosis (DVT) after surgery was observed. The expression of inflammatory factors and the improvement of cognitive function were assessed before surgery, followed by 6 and 12 h after surgery. The pain degree of patients was compared at 6 and 12 h after surgery.

resultsCompared with the CG, the recovery condition after surgery in the RG were dramatically lower, the concentrations of PLT, PT, and APTT in the RG were higher, while FBG was markedly lower. The incidence of postoperative venous thrombosis in the RG was lower. The TNF-α, IL-6 levels, and VAS scores in the RG were remarkably lower at 6 and 12 h after surgery. MMSE score was significantly higher than CG score. The total incidence of adverse reactions in the RG was markedly lower.

conclusionEpidural anesthesia can improve blood coagulation and cognitive function in patients undergoing TKA and reduce the incidence of DVT and the degree of postoperative pain.

Indexed as

coagulation functionEpidural anesthesiageneral anesthesiatotal knee arthroplasty

Identifiers

PMID34650774

PMCPMC8507049

OpenAlexW3205834515

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.