Evidence map›Paper›PMID 34651238›Full record

ArticleLangenbeck's archives of surgery2022

GLP-1: 10-year follow-up after Roux-en-Y gastric bypass.

Camila Carvalho, Aglécio Luiz de Souza, Gisele Almeida Batista, Louise Franciscato Trivelato Duran, Débora Puzzi Fernandes, Viviane Bressane Claus Molina, Raquel Gonçalves, Joelma Silvia Giorgetti, Elintom Adami Chaim, Sarah Monte Alegre

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In one paragraph

Article in Langenbeck's archives of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Camila CarvalhoDepartment of Internal Medicine, School of Medical Sciences, PO, University of Campinas-UNICAMP, Campinas, SP, 13083-970, Brazil. carvalhopcami@yahoo.com.br.ORCID http://orcid.org/0000-0001-9043-4934
Aglécio Luiz de SouzaDepartment of Internal Medicine, School of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Gisele Almeida BatistaDepartment of Internal Medicine, School of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Louise Franciscato Trivelato DuranDepartment of Internal Medicine, School of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Débora Puzzi FernandesDepartment of Internal Medicine, School of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Viviane Bressane Claus MolinaDepartment of Internal Medicine, School of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Raquel GonçalvesDepartment of Internal Medicine, School of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Joelma Silvia GiorgettiDepartment of Internal Medicine, School of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Elintom Adami ChaimSurgery Department, School of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Sarah Monte AlegreDepartment of Internal Medicine, School of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGlucagon-like peptide-1 (GLP-1) is a hormone widely studied in the short-term postoperative follow-up of Roux-en-Y gastric bypass due to its elevation and association with improvement of the glucose metabolism, but there are few studies in 10 years after RYGB follow-up with the same patient.

methodsTwenty morbidity obesity patients were submitted to RYGB; these patients were divided into two groups: normal glucose-tolerant morbidly obese patients (NGT) 11 patients and abnormal glucose metabolism morbidly obese patients (AGM) 9 patients. Oral glucose tolerance test (OGTT) was done during four different periods: T1 (first evaluation), T2 (pre-surgery), T3 (9 months after surgery) and T4 (10 years after surgery).

resultsGroups were matched for age and gender, and as NGT and AGM had BMI of 46.31 ± 5.03 kg/m

conclusionEvaluation of the same patient during 4 different periods shows that, even with weight regain, after 10-years of RYGB high levels of GLP-1 remained which can be associated with metabolic improvement especially at the NGT group.

Indexed as

Gastric BypassObesity, MorbidBlood GlucoseFollow-Up StudiesGlucagon-Like Peptide 1HumansBlood GlucoseGlucagon-Like Peptide 1GLP-1Glucose metabolismInsulin resistanceObesityRYGBWeight regain

Identifiers

PMID34651238
OpenAlexW3205179831

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.