Evidence map›Paper›PMID 34652685›Full record

ArticleCell biochemistry and biophysics2021

Generation of an Lpar1-EGFP Fusion Knock-in Transgenic Mouse Line.

Richard Rivera, Nyssa A Williams, Grace G Kennedy, Paloma Sánchez-Pavón, Jerold Chun

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell biochemistry and biophysics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Generation of New Knock-Out Mouse Strains ofInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Richard RiveraTranslational Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6138-3306
Nyssa A WilliamsTranslational Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Grace G KennedyTranslational Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Paloma Sánchez-PavónTranslational Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-9530-1337
Jerold ChunTranslational Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA. jchun@sbpdiscovery.org.ORCID http://orcid.org/0000-0003-3964-0921
Sanford Burnham Prebys Medical Discovery Institute · US

Funding

Tumor Microenvironment and Cancer ImmunologyP30CA030199 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI ELENA B PASQUALE · 1985 to 2026
$107.2M
Prenatal blood-borne lipids in post-hemorrhagic hydrocephalusR01NS084398 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI CHUN, JEROLD · 2014 to 2017
$2.6M
Clause Scholarship Program in Neurodegeneration and Aging Predoctoral FellowshipNCI NIH HHS P30 CA030199NINDS NIH HHS R01 NS084398NINDS NIH HHS R01NS084398U.S. Department of Defense W81XWH-17-1-0455
6 · The paper itself

Abstract

Lysophosphatidic acid (LPA) is a lysophospholipid that acts as an extracellular signal through the activation of cognate G protein-coupled receptors (GPCRs). There are six known LPA receptors (LPA

Indexed as

Gene Knock-In TechniquesGreen Fluorescent ProteinsReceptors, Lysophosphatidic AcidAllelesAnimalsCentral Nervous SystemEmbryonic Stem CellsFemaleMaleMiceMice, TransgenicRecombinant Fusion Proteinsenhanced green fluorescent proteinGreen Fluorescent ProteinsLPAR1 protein, mouseReceptors, Lysophosphatidic AcidRecombinant Fusion Proteins

Identifiers

PMID34652685
PMCPMC8551097
OpenAlexW3205847532

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.