ArticleScience immunology2021
Lymph node-resident dendritic cells drive T
Open access · greenAbstract read
In one paragraph
Article in Science immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 22 citations in OpenAlex.
- MAGUK p55 subfamily member 7 attenuates allergic airway inflammation by modulating lung dendritic cells functions.Scientific reports · 2026Article
- MARCH2 suppresses odontoblast differentiation by polyubiquitinating PTPRD.International journal of oral science · 2026Article
- Dendritic Cells in the Gastrointestinal System: Division of Labor, Plasticity, and Niche-Specific Adaptation.Immunological reviews · 2026Review
- USP18 confers protection against allergic asthma by suppressing CCL8 production in alveolar type II epithelial cells.Respiratory research · 2025Article
- Ontogenetic Diversification of Type 2 Conventional Dendritic Cells in the Bone Marrow: A Central Logic for Peripheral Immunity.Immunological reviews · 2025Review
- Ubiquitination regulates allergic asthma by affecting immune cells and immune responses.Biochemistry and biophysics reports · 2025Review
- Dendritic cells steering antigen and leukocyte traffic in lymph nodes.FEBS letters · 2025Review
- How type-2 dendritic cells induce Th2 differentiation: Instruction, repression, or fostering T cell-T cell communication?Allergy · 2025Review
- Gene expression and alternative splicing analysis in a large-scale Multiple Sclerosis study.medRxiv : the preprint server for health sciences · 2024Article
- Macro-clusters: CD301b+ DCs prime Th2 responses.The Journal of experimental medicine · 2024Article
- Site-specific regulation of Th2 differentiation within lymph node microenvironments.The Journal of experimental medicine · 2024Article
- Regulation of MHC class II and CD86 expression by March-I in immunity and disease.Current opinion in immunology · 2023Review
- Thiolutin attenuates ischemic stroke injury via inhibition of NLRP3 inflammasome: an in vitro and in vivo study.Experimental brain research · 2023Article
- Metabolic requirements of Th17 cells and of B cells: Regulation and defects in health and in inflammatory diseases.Frontiers in immunology · 2022Review
- Targeting psychological stress-steroid-MARCH1 signaling pathway promotes the efficacy of specific allergen immunotherapy.Theranostics · 2022Article
- Post-Translational Modifications in Atopic Dermatitis: Current Research and Clinical Relevance.Frontiers in cell and developmental biology · 2022Review
- Granulocyte Macrophage-Colony Stimulating Factor Produces a Splenic Subset of Monocyte-Derived Dendritic Cells That Efficiently Polarize T Helper Type 2 Cells in Response to Blood-Borne Antigen.Frontiers in immunology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 7 institutions in 3 countries.
Carlos A CastellanosDepartment of Microbiology and Immunology, Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-3615-2009
Xin RenDepartment of Medicine, Lung Biology Center, University of California, San Francisco, San Francisco, CA 94158, USA.
Steven Lomeli GonzalezDepartment of Microbiology and Immunology, Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA.
Hong Kun LiDepartment of Microbiology and Immunology, Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA.
Andrew W SchroederDepartment of Pulmonology, Genomics CoLabs, University of California, San Francisco, San Francisco, CA 94158, USA.
Hong-Erh LiangDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-0620-7224
Brian J LaidlawDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.
Donglei HuDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0002-0351-001X
Angel C Y MakDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0002-5372-4198
Celeste EngDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0001-7968-1862
José R Rodríguez-SantanaCentro de Neumología Pediátrica, San Juan, Puerto Rico 00917, USA.
Michael LeNoirBay Area Pediatrics, Oakland, CA 94609, USA.
Qi YanDepartment of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, NY 10032, USA.ORCID 0000-0002-5236-9673
Juan C CeledónDivision of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA 15224, USA.ORCID 0000-0002-6139-5320
Esteban G BurchardDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0001-7475-2035
Scott S ZamvilDepartment of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0003-2720-9915
Satoshi IshidoDepartment of Microbiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan.ORCID 0000-0001-5893-3354
Richard M LocksleyDepartment of Medicine, Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-5468-6867
Jason G CysterDepartment of Microbiology and Immunology, Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-4735-9745
Xiaozhu HuangDepartment of Medicine, Lung Biology Center, University of California, San Francisco, San Francisco, CA 94158, USA.
Jeoung-Sook ShinDepartment of Microbiology and Immunology, Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-0711-8234
University of California, San Francisco · USHoward Hughes Medical Institute · USCentro de Neumologia Pediatrica · PRColumbia University Irving Medical Center · USEast Bay Educational Collaborative · USHyogo Medical University · JPUniversity of Pittsburgh · US
Funding
Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1MNew York Center for Collaborative Research In Common Disease Genomics: Genome Aggregation and Joint Variant Calling for CCDG Freeze2UM1HG008901 · NHGRI · NEW YORK GENOME CENTER · PI MANIATIS, THOMAS P, WIGLER, MICHAEL H · 2016 to 2020
$56.6MMOLECULAR AND CELLULAR IMMUNOLOGYT32AI007334 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CYSTER, JASON G · 1988 to 2023
$11.0MStudies of Rare Genetic Variation in the Isolated Population of SardiniaR01HL117626 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ABECASIS, GONCALO · 2013 to 2016
$10.5MThe Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with AsthmaR01HL117004 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, SEIBOLD, MAX A · 2013 to 2022
$9.3MRare variants and NHLBI traits in deeply phenotyped cohortsR01HL120393 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M, RICE, KENNETH M. · 2014 to 2016
$8.9MSF BUILD: Enabling Students to Represent in ScienceTL4GM118986 · NIGMS · SAN FRANCISCO STATE UNIVERSITY · PI MARQUEZ-MAGANA, LETICIA MARIA, MORRIS, MEGHAN D · 2015 to 2022
$5.4MNHGRI Genome Sequencing Program Coordinating CenterU24HG008956 · NHGRI · RUTGERS, THE STATE UNIV OF N.J. · PI BUYSKE, STEVEN G, MATISE, TARA C. · 2016 to 2020
$4.9MGenes, air pollution, and asthma severity in minority childrenR01MD010443 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEIBOLD, MAX A, ZIV, ELAD · 2016 to 2020
$3.8MParasite immunity orchestrated by type 2 immune cellsR01AI026918 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LOCKSLEY, RICHARD M · 1988 to 2022
$3.8MRepertoire selection of AQP4-specific T cells that cause CNS autoimmunediseaseR01AI131624 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ZAMVIL, SCOTT S · 2019 to 2023
$2.2MRole of MARCH1 E3 ubiquitin ligase in thymic dendritic cell functionR01GM105800 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHIN, JEOUNG-SOOK · 2013 to 2017
$1.5MNCATS NIH HHS UL1 TR001872NHGRI NIH HHS U24 HG008956NHGRI NIH HHS UM1 HG008901NHLBI NIH HHS HHSN268201800001CNHLBI NIH HHS R01 HL117004NHLBI NIH HHS R01 HL117626NHLBI NIH HHS R01 HL120393NIAID NIH HHS R01 AI026918NIAID NIH HHS R01 AI131624NIAID NIH HHS T32 AI007334NIEHS NIH HHS HHSN268201600032CNIGMS NIH HHS R01 GM105800NIGMS NIH HHS R35 GM131702NIGMS NIH HHS TL4 GM118986NIMHD NIH HHS R01 MD010443
Abstract
Type 2 T helper (T
Indexed as
AnimalsDendritic CellsLymph NodesMiceMice, Inbred C57BLMice, KnockoutTh2 CellsUbiquitin-Protein LigasesMARCH1 protein, mouseUbiquitin-Protein Ligases
Identifiers
What Socratic holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.