SynthesisFrontiers in endocrinology2021
COVID-19-Associated Subacute Thyroiditis: Evidence-Based Data From a Systematic Review.
Synthesis in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 4 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Thyroxine changes in COVID-19 pandemic: A systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Subacute thyroiditis following COVID-19: A systematic review.Frontiers in endocrinology · 2023Pooled it
- ESCMID rapid guidelines for assessment and management of long COVID.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022Guideline
- SARS-CoV-2 vaccine-associated subacute thyroiditis: insights from a systematic review.Journal of endocrinological investigation · 2022Pooled it
- Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights.Endocrinology, diabetes & metabolism · 2026Review
- COVID-19 pandemic and thyroid diseases.Frontiers in endocrinology · 2026Article
- Traditional Chinese Medicine as an Adjunct in Hyperthyroidism Management: A Narrative Review of Pathophysiology, Proposed Mechanisms, and Clinical Evidence.International journal of general medicine · 2026Review
- Post-COVID-19 subacute painless thyroiditis: a case report in an anabolic androgenic steroid user.BMC infectious diseases · 2025Article
- Subacute thyroiditis after COVID-19 - Clinical, laboratory and ultrasound aspects.Journal of family medicine and primary care · 2025Article
- Primary Burkitt Lymphoma of the Thyroid Associated With Hashimoto Thyroiditis Masquerading as Post-COVID Thyroiditis.JCEM case reports · 2025Article
- Assessment of Thyroid Status and Six Months of Follow-Up in COVID-19 Patients: A Prospective, Observational Study.Cureus · 2025Article
- Thyroiditis and COVID-19: focus on pediatric age. A narrative review.Journal of endocrinological investigation · 2024Review
- The Potential Role of Virus Infection in the Progression of Thyroid Cancer.World journal of oncology · 2024Review
- Subacute Thyroiditis Following COVID-19: A Case of Diagnostic Challenge in the Absence of Neck Pain.Cureus · 2024Article
- Fever and Neck Pain in an Adolescent: A Case Report.Clinical pediatrics · 2024Article
- Subacute thyroiditis after SARS-CoV-2 vaccination: A case report.Clinical case reports · 2024Article
- Subacute Thyroiditis in Active COVID-19 Infection: A Report of Two Cases With a Systematic Review of the Literature.Cureus · 2024Article
- Insights into SARS-CoV-2-associated subacute thyroiditis: from infection to vaccine.Virology journal · 2023Review
- Effect of the COVID-19 pandemic on surgery for indeterminate thyroid nodules (THYCOVID): a retrospective, international, multicentre, cross-sectional study.The lancet. Diabetes & endocrinology · 2023Article
- HLA typing of patients who developed subacute thyroiditis and Graves' disease after SARS-CoV-2 vaccination: a case report.BMC endocrine disorders · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subacute thyroiditis (SAT) is a thyroid disease of viral or post-viral origin. Whether SAT represents a complication of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still unclear. Our aim was to systematically review the literature to 1) explore the size of the literature about SAT in COVID-19 and 2) evaluate the clinical characteristics of SAT. PubMed/MEDLINE, Embase, and Scopus were searched until April 20, 2021. Original papers, case reports, and case series reporting SAT in COVID-19 patients were included. Authors and their country, journal, year of publication, COVID-19 and SAT clinical presentation, thyroid function, therapy, and follow-up data were extracted. Nineteen papers (17 case reports and 2 case series) were included, describing 27 patients, 74.1% females, aged 18 to 69 years. COVID-19 was diagnosed by nasopharyngeal swab in 66.7% cases and required hospitalization in 11.1%. In 83.3% cases, SAT occurred after COVID-19. Neck pain was present in 92.6% cases and fever in 74.1%. Median TSH, fT3, and fT4 were 0.01 mU/l, 10.79 pmol/l, and 27.2 pmol/l, respectively. C-reactive-protein and erythrocyte sedimentation rate were elevated in 96% of cases. Typical ultrasonographic characteristics of SAT were observed in 83.3% of cases. Steroids were the most frequent SAT therapy. Complete remission of SAT was recorded in most cases. In conclusion, the size and quality of published data of SAT in COVID-19 patients are poor, with only case reports and case series being available. SAT clinical presentation in COVID-19 patients seems to be similar to what is generally expected.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.