Evidence map›Paper›PMID 34660669›Full record

ArticleFrontiers in nutrition2021

Coral-Derived Endophytic Fungal Product, Butyrolactone-I, Alleviates Lps Induced Intestinal Epithelial Cell Inflammatory Response Through TLR4/NF-κB and MAPK Signaling Pathways: An

Shengwei Chen, Yi Zhang, Xueting Niu, Sahar Ghulam Mohyuddin, Jiayin Wen, Minglong Bao, Tianyue Yu, Lianyun Wu, Canyin Hu, Yanhong Yong and 3 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Identification of Peptides from EdibleFoods (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Review
  6. Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future.Drug metabolism and disposition: the biological fate of chemicals · 2023
    Review
  7. Article
  8. Article
  9. Butenolide derivatives fromFrontiers in chemistry · 2022
    Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 3 countries.

Shengwei ChenDepartment of Veterinary Medicine, Guangdong Ocean University, Zhanjiang, China.
Yi ZhangShenzhen Institute of Guangdong Ocean University, Shenzhen, China.
Xueting NiuDepartment of Veterinary Medicine, Guangdong Ocean University, Zhanjiang, China.
Sahar Ghulam MohyuddinDepartment of Veterinary Medicine, Guangdong Ocean University, Zhanjiang, China.
Jiayin WenDepartment of Veterinary Medicine, Guangdong Ocean University, Zhanjiang, China.
Minglong BaoDepartment of Veterinary Medicine, Guangdong Ocean University, Zhanjiang, China.
Tianyue YuDepartment of Veterinary Medicine, Guangdong Ocean University, Zhanjiang, China.
Lianyun WuDepartment of Veterinary Medicine, Guangdong Ocean University, Zhanjiang, China.
Canyin HuDepartment of Veterinary Medicine, Guangdong Ocean University, Zhanjiang, China.
Yanhong YongDepartment of Veterinary Medicine, Guangdong Ocean University, Zhanjiang, China.
Xiaoxi LiuShenzhen Institute of Guangdong Ocean University, Shenzhen, China.
A M Abd El-AtyState Key Laboratory of Bio Based Material and Green Papermaking, College of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Science, Jinan, China.
Xianghong JuDepartment of Veterinary Medicine, Guangdong Ocean University, Zhanjiang, China.
Guangdong Ocean University · CNCairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we assessed the anti-inflammatory and intestinal barrier protective effects of butyrolactone-I (BTL-1), derived from the coral-derived endophytic fungus (

Indexed as

anti-inflammatorybutyrolactone-IIBDintestinal barrierMAPKTLR4/NF-κB

Identifiers

PMID34660669
PMCPMC8517189
OpenAlexW3201796766

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.