Evidence map›Paper›PMID 34675018›Full record

ArticleBMJ open2021

Video game therapy on mobility and dual tasking in multiple sclerosis: study protocol for a randomised controlled trial.

Andrea Baroni, Giulia Fregna, Giada Milani, Giacomo Severini, Giulia Zani, Nino Basaglia, Sofia Straudi

2 registry-linked trialsOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03353974 nacompletednot on this map

The Role of Video Games Therapy on Balance and Cognitive Functions in Mild to Moderate Impaired Multiple Sclerosis Patients. A Pilot Randomized Controlled Trial.

TypeinterventionalSponsorUniversity Hospital of FerraraRan2017 to 2022Enrolled48ConditionsMultiple SclerosisArmsVideo game therapy, Balance platform therapy
NCT06485115 naunknown statusnot on this mapstarted 2024, after this paper: background citation

The Effectiveness of Combining a Home-based Digital Motor Telerehabilitation Program With Conventional Therapy in Progressive Multiple Sclerosis: a Multicentre, Randomized Controlled Trial

TypeinterventionalSponsorUniversita di VeronaRan2024 to 2026Enrolled78ConditionsProgressive Multiple SclerosisArmsDigital Telerehabilitation (Euleria Home), Conventional therapy
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Andrea BaroniDepartment of Neuroscience and Rehabilitation, Ferrara University Hospital, Ferrara, Italy.
Giulia FregnaDepartment of Neuroscience and Rehabilitation, Ferrara University Hospital, Ferrara, Italy.
Giada MilaniDoctoral Program in Translational Neurosciences and Neurotechnologies, University of Ferrara, Ferrara, Italy.
Giacomo SeveriniSchool of Electrical and Electronic Engineering, University College Dublin, Dublin, Ireland.
Giulia ZaniDepartment of Neuroscience and Rehabilitation, Ferrara University Hospital, Ferrara, Italy.
Nino BasagliaDepartment of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy.
Sofia StraudiDepartment of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy s.straudi@ospfe.it.ORCID 0000-0002-2061-9922
University of Ferrara · ITUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMultiple sclerosis (MS) is one of the major causes of disability in young adults and affects mobility, compromising daily living activities and participation in social life. Cognitive domain is also frequently impaired in people with MS (PwMS), particularly the capacity to perform dual-task activities. Impaired cognitive processing abilities need to be treated, and motor and cognitive aspects need to be considered together. Recently, video game therapy (VGT) has been used in rehabilitation to improve motor outcomes and cognitive processing speed. The aim of this study is to test the efficacy of commercially available VGT on mobility and dual tasking in PwMS compared with standardised balance platform training (BPT). METHODS AND ANALYSIS: This will be a parallel-assignment, double-blinded, randomised control trial. Forty-eight (24 per arm) PwMS with Expanded Disability Status Scale 4-5.5 will be randomly assigned to receive 1 hour training session over 4 weeks (three sessions/week) of either: (1) VGT on commercial video game console to train balance and mobility-related activities or (2) BPT to perform balance, postural stability and weight-shifting exercises with and without visual feedback. The same assessor will evaluate outcome measures at points: before and after the 12 training sessions and at 3 months of follow-up. The primary outcome will be functional mobility, assessed by the Timed Up and Go test. We will also evaluate gait, risk of fall, fatigue and health-related quality of life as well as cognitive and psychological aspects (depression, anxiety and attentional performance) and stability through posturographic evaluation. Dual-tasking assessment will be performed combining posturographic and neuropsychological tests. Data analysis will be performed to compare the efficacy of the two treatments. ETHICS AND DISSEMINATION: Ethical approval have been granted from the local Ethics Committee. Study results will be communicated through high-quality journals and national and international conferences. TRIAL REGISTRATION NUMBER: NCT03353974.

Indexed as

Multiple SclerosisVideo GamesExercise TherapyHumansPostural BalanceQuality of LifeRandomized Controlled Trials as TopicTime and Motion StudiesYoung AdultMultiple sclerosisrehabilitation medicinestatistics & research methods

Identifiers

PMID34675018
PMCPMC8532542
OpenAlexW3207073662

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.