Evidence map›Paper›PMID 34677465›Full record

ArticleMarine drugs2021

Targeted Isolation of a Cytotoxic Cyclic Hexadepsipeptide from the Mesophotic Zone Sponge-Associated Fungus

Ye Yuan, Te Li, Tingting Wang, C Benjamin Naman, Jing Ye, Xingxin Wu, J Enrico H Lazaro, Xiaojun Yan, Shan He

Abstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ye YuanDepartment of Marine Pharmacy, Li Dak Sum Marine Biopharmaceutical Research Center, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315832, China.
Te LiDepartment of Marine Pharmacy, Li Dak Sum Marine Biopharmaceutical Research Center, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315832, China.
Tingting WangDepartment of Marine Pharmacy, Li Dak Sum Marine Biopharmaceutical Research Center, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315832, China.
C Benjamin NamanDepartment of Marine Pharmacy, Li Dak Sum Marine Biopharmaceutical Research Center, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315832, China.ORCID 0000-0002-4361-506X
Jing YeState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Xingxin WuState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.ORCID 0000-0003-0834-4601
J Enrico H LazaroNational Institute of Molecular Biology and Biotechnology, University of the Philippines Diliman, Quezon 1101, Philippines.
Xiaojun YanSchool of Marine Science, Ningbo University, Ningbo 315832, China.ORCID 0000-0003-0257-0157
Shan HeDepartment of Marine Pharmacy, Li Dak Sum Marine Biopharmaceutical Research Center, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315832, China.ORCID 0000-0002-0196-7278

Funding

National 111 Project of China D16013National Natural Science Foundation of China 41906093National Natural Science Foundation of China 42176101Natural Science Foundation of Zhejiang Province LGF21D060003
6 · The paper itself

Abstract

LC-MS/MS-based molecular networking facilitated the targeted isolation of a new cyclic hexadepsipeptide, cymodepsipeptide (

Indexed as

AnimalsAntineoplastic AgentsAquatic OrganismsCell Line, TumorChromatography, LiquidDrug Screening Assays, AntitumorHumansHypocrealesPeptides, CyclicPoriferaTandem Mass SpectrometryAntineoplastic AgentsPeptides, Cycliccytotoxicityhexadepsipeptidemesophotic zonesponge-associated fungisponges

Identifiers

PMID34677465
PMCPMC8540034

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.