Trial reportPloS one2021
Effects of intradialytic exercise for advanced-age patients undergoing hemodialysis: A randomized controlled trial.
Trial report in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06137937 (Intradialytic Aerobic Exercise in CKD Patient), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intradialytic Aerobic Exercise in CKD Patient
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Effects of Exercise on Sarcopenia and Frailty in Haemodialysis Patients: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- The effect of intradialytic resistance exercise on physical function and dialysis adequacy in patients on maintenance hemodialysis.PloS one · 2026Trial
- Addition of Neuromuscular Electrical Stimulation, Based on the Level of Excitability, to an Intradialytic Twice-Weekly Cycling Protocol: A Randomized Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Trial
- Oral creatine in hemodialysis patients increases physical functional capacity and muscle mass, an open label study.PloS one · 2025Trial
- A Randomized Controlled Trial of Whole-Body Vibration on Gait Ability and Balance among Older Hemodialysis Patients.Clinical journal of the American Society of Nephrology : CJASN · 2023Trial
- Does Intradialytic Group Exercise Programme Influence Patient-Reported Outcomes, Laboratory Parameters, and Anthropometric Parameters in Maintenance Hemodialysis Patients? A Single-Group Repeated-Measures Trial.Patient preference and adherence · 2023Trial
- Ten tips on how to prevent falls in dialysis patients.Clinical kidney journal · 2026Review
- Systematic Review of Exercise Training and Musculoskeletal Health in Patients Receiving Dialysis.Kidney international reports · 2026Article
- The Influence of Aerobic and Strength Training on Oxidative Stress and Antioxidant Status in Hemodialysis Patients: A Randomized Controlled Trial.Health science reports · 2026Article
- Perceptions of Exercise Benefits and Barriers and Physical Activity Status Among Patients Undergoing Hemodialysis in Saudi Arabia.Healthcare (Basel, Switzerland) · 2026Article
- Effectiveness of Physiotherapy in Haemodialysis: Systematic Review.Life (Basel, Switzerland) · 2026Review
- Physical activity levels and mortality in peritoneal dialysis patients.BMC nephrology · 2025Article
- Factors Influencing Recruitment, Retention, and Adherence Rates in Exercise Interventions in ESKD: A Scoping Review.Kidney medicine · 2025Article
- The impact of malnutrition on the effectiveness of intradialytic exercise in hemodialysis patients: amulticenter cohort study.International urology and nephrology · 2024Article
- The Impact of Diabetes Complications on the Physical Function of Maintenance Hemodialysis Patients.Cureus · 2024Article
- Low muscle strength and physical function contribute to falls in hemodialysis patients, but not muscle mass.Clinical and experimental nephrology · 2024Article
- Age and sex differences in the effectiveness of intradialytic resistance training on muscle function.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous reports have shown the benefits of intradialytic exercise to patients undergoing hemodialysis. However, most of those studies assessed the effects of exercise in middle-aged patients and little is known about advanced-age patients undergoing hemodialysis. Therefore, the present randomized controlled trial was performed to determine the effectiveness of exercise therapy in advanced-age patients undergoing hemodialysis. This non-blinded, randomized controlled parallel trial enrolled a total of 101 patients who were randomly assigned to intradialytic exercise (n = 51) or usual care (n = 50) groups. The training program included both resistance and aerobic exercises and was performed three times per week for 6 months. The aerobic exercise intensity was adjusted to a target Borg score of 13 for 20 minutes. Four types of resistance exercises were performed using elastic tubing, with three sets of 10 exercises performed at moderate intensity (13/20 on the Borg scale). The usual care group received standard care. Lower extremity muscle strength, Short Physical Performance Battery score, and 10-m walking speed were the outcomes and were evaluated before the hemodialysis session and after 6 months of training. There were statistically significant improvements in Short Physical Performance Battery score (effect size, 0.57; 95% confidence interval, 0.15‒1.95) in the exercise group relative to the control group. There were no statistically significant differences in lower extremity muscle strength or in the 10-m walking speed between the two groups. These findings suggest that 6 months of intradialytic training could improve physical function in older patients undergoing hemodialysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.