Evidence map›Paper›PMID 34679705›Full record

ReviewAntioxidants (Basel, Switzerland)2021

Mechanistic Aspects of Apiaceae Family Spices in Ameliorating Alzheimer's Disease.

Niti Sharma, Mario A Tan, Seong Soo A An

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Neurotrophic Effects ofInternational journal of molecular sciences · 2024
    Article
  4. Review
  5. Neuroprotection byInternational journal of molecular sciences · 2024
    Article
  6. Article
  7. Multi-Targeting Neuroprotective Effects ofInternational journal of molecular sciences · 2023
    Article
  8. Antioxidant Activity ofAntioxidants (Basel, Switzerland) · 2022
    Review
  9. IBRO neuroscience reports · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Niti SharmaDepartment of Bionano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-Gu, Seongnam 461-701, Korea.ORCID 0000-0001-6720-257X
Mario A TanCollege of Science and Research Center for the Natural and Applied Sciences, University of Santo Tomas, Manila 1015, Philippines.
Seong Soo A AnDepartment of Bionano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-Gu, Seongnam 461-701, Korea.
Gachon University · KRUniversity of Santo Tomas · PH

Funding

Basic Science Research Program South Korea 2021R1A6A1A03038996National Research Foundation of Korea NRF 2020R1A2B5B01002463
6 · The paper itself

Abstract

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases worldwide. In an effort to search for new strategies for treating AD, natural products have become candidates of choice. Plants are a rich source of bioactive and effective compounds used in treating numerous diseases. Various plant extracts are known to display neuroprotective activities by targeting different pathophysiological pathways in association with the diseases, such as inhibiting enzymes responsible for degrading neurotransmitters, reducing oxidative stress, neuroprotection, inhibiting amyloid plaque formation, and replenishing mitochondrial function. This review presented a comprehensive evaluation of the available scientific literature (in vivo, in vitro, and in silico) on the neuroprotective mechanisms displayed by the extracts/bioactive compounds from spices belonging to the Apiaceae family in ameliorating AD.

Indexed as

Alzheimer’s diseaseamyloid-betaantioxidantenzyme inhibitorsessential oilsnatural productsneuroprotectivespices

Identifiers

PMID34679705
PMCPMC8533116
OpenAlexW3202121297

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.