Evidence mapPaperPMID 34680583Full record

ReviewBiomedicines2021

Essential Fatty Acids as Biomedicines in Cardiac Health.

Igori Balta, Lavinia Stef, Ioan Pet, Tiberiu Iancu, Ducu Stef, Nicolae Corcionivoschi

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 64 citations in OpenAlex.

  1. Buckwheat (Journal of agricultural and food chemistry · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Nutritional and Bioactive Profiling ofMolecules (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Multiple Roles of Palmitic Acid in Cardiovascular Diseases.Journal of inflammation research · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Fatty Acid Profiles in the Gonads of Red King Crab (Animals : an open access journal from MDPI · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Igori BaltaBacteriology Branch, Veterinary Sciences Division, Agri-Food and Biosciences Institute, Belfast BT4 3SD, UK.ORCID 0000-0002-1171-2623
Lavinia StefFaculty of Bioengineering of Animal Resources, Banat University of Animal Sciences and Veterinary Medicine-King Michael I of Romania, 300645 Timisoara, Romania.
Ioan PetFaculty of Bioengineering of Animal Resources, Banat University of Animal Sciences and Veterinary Medicine-King Michael I of Romania, 300645 Timisoara, Romania.
Tiberiu IancuFaculty of Management and Rural Development, Banat University of Animal Sciences and Veterinary Medicine-King Michael I of Romania, 300645 Timisoara, Romania.
Ducu StefFaculty of Food Processing Technologies, Banat University of Animal Sciences and Veterinary Medicine-King Michael I of Romania, 300645 Timisoara, Romania.
Nicolae CorcionivoschiBacteriology Branch, Veterinary Sciences Division, Agri-Food and Biosciences Institute, Belfast BT4 3SD, UK.ORCID 0000-0002-3011-3108
Univesity of Life Science "King Mihai I" from Timisoara · ROAgri Food and Biosciences Institute · GBUniversity of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The destructive impact of cardiovascular diseases on health, including heart failure, peripheral artery disease, atherosclerosis, stroke, and other cardiac pathological conditions, positions these health conditions as leading causes of increased global mortality rates, thereby impacting the human quality of life. The considerable changes in modern lifestyles, including the increase in food intake and the change in eating habits, will unavoidably lead to an unbalanced consumption of essential fatty acids, with a direct effect on cardiovascular health problems. In the last decade, essential fatty acids have become the main focus of scientific research in medical fields aiming to establish their impact for preventing cardiovascular diseases and the associated risk factors. Specifically, polyunsaturated fatty acids (PUFA), such as omega 3 fatty acids, and monounsaturated fatty acids from various sources are mentioned in the literature as having a cardio-protective role, due to various biological mechanisms that are still to be clarified. This review aims to describe the major biological mechanisms of how diets rich in essential fatty acids, or simply essential fatty acid administration, could have anti-inflammatory, vasodilatory, anti-arrhythmic, antithrombotic, antioxidant, and anti-atherogenic effects. This review describes findings originating from clinical studies in which dietary sources of FAs were tested for their role in mitigating the impact of heart disorders in human health.

Indexed as

cardiac healthcardiovascular diseasesEPA and DHAessentially fatty acidsfatty acid sourcesmolecular mechanismsomega-3PFAsymptom relief

Identifiers

PMID34680583
PMCPMC8533423
OpenAlexW3206796315

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.