Evidence map›Paper›PMID 34683124›Full record

ArticleJournal of personalized medicine2021

Knockout of Hepatocyte Growth Factor by CRISPR/Cas9 System Induces Apoptosis in Hepatocellular Carcinoma Cells.

Han Ki Lee, Heui Min Lim, See-Hyoung Park, Myeong Jin Nam

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Light-Triggered CRISPR/Cas12a for Genomic Editing and Tumor Regression.Angewandte Chemie (International ed. in English) · 2025
    Article
  3. Review
  4. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Han Ki LeeDepartment of Biological Science, Gachon University, Seongnam 13120, Korea.
Heui Min LimDepartment of Biological Science, Gachon University, Seongnam 13120, Korea.ORCID 0000-0003-3229-2186
See-Hyoung ParkDepartment of Bio and Chemical Engineering, Hongik University, Sejong 30016, Korea.ORCID 0000-0003-0020-7389
Myeong Jin NamDepartment of Biological Science, Gachon University, Seongnam 13120, Korea.
Gachon University · KRHongik University · KR

Funding

National Research Foundation of Korea NRF-2014R1A6A3A04054307
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

apoptosisc-Met signaling pathwayCRISPR/Cas9 systemhepatocellular carcinomahepatocyte growth factormitogen activated protein kinases

Identifiers

PMID34683124
PMCPMC8540514
OpenAlexW3203206704

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.