Evidence map›Paper›PMID 34684456›Full record

ArticleNutrients2021

Association of Sodium, Potassium and Sodium-to-Potassium Ratio with Urine Albumin Excretion among the General Chinese Population.

Yuewen Sun, Puhong Zhang, Yuan Li, Feng J He, Jing Wu, Jianwei Xu, Xiaochang Zhang, Xian Li, Jing Song

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Yuewen SunThe George Institute for Global Health at Peking University Health Science Centre, Beijing 100600, China.ORCID 0000-0002-1681-4848
Puhong ZhangThe George Institute for Global Health at Peking University Health Science Centre, Beijing 100600, China.ORCID 0000-0003-4610-9848
Yuan LiThe George Institute for Global Health at Peking University Health Science Centre, Beijing 100600, China.ORCID 0000-0003-1887-7065
Feng J HeWolfson Institute of Preventive Medicine, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.ORCID 0000-0003-2807-4119
Jing WuThe National Center for Chronic and Noncommunicable Disease Control and Prevention, The Chinese Center for Disease Control and Prevention, Beijing 100000, China.
Jianwei XuThe National Center for Chronic and Noncommunicable Disease Control and Prevention, The Chinese Center for Disease Control and Prevention, Beijing 100000, China.
Xiaochang ZhangNoncommunicable Disease and Aging Health Management Division, Chinese Center for Disease Control and Prevention, Beijing 100000, China.
Xian LiThe George Institute for Global Health at Peking University Health Science Centre, Beijing 100600, China.
Jing SongWolfson Institute of Preventive Medicine, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
Peking University · CNNational Center for Chronic and Noncommunicable Disease Control and Prevention · CNQueen Mary University of London · GBChinese Center For Disease Control and Prevention · CN

Funding

National Institute for Health Research 16/136/77
6 · The paper itself

Abstract

Mixed evidence was published regarding the association of sodium, potassium and sodium-to-potassium ratio (Na/K ratio) with renal function impairment. This study was conducted to further explore the relationship between sodium, potassium, NA/K ratio and kidney function in the general adult Chinese population. We performed a cross-sectional analysis using the baseline data from the Action on Salt China (ASC) study. 5185 eligible general adult participants from the baseline investigation of the ASC study were included in this analysis. Sodium, potassium and albumin excretion were examined from 24-h urine collection. Albuminuria was defined as albumin excretion rate (AER) greater than or equal to 30 mg/24-h. Mixed linear regression models, adjusted for confounders, were fitted to analyze the association between sodium, potassium and Na/K ratio, and natural log transformed AER. Mixed effects logistic regression models were performed to analyze the odds ratio of albuminuria at each quintile of sodium, potassium and Na/K ratio. The mean age of the participants was 49.5 ± 12.8 years, and 48.2% were male. The proportion of albuminuria was 7.5%.The adjusted mixed linear models indicated that sodium and Na/K ratio was positively associated with natural log transformed AER (Sodium: β = 0.069, 95%CI [0.050, 0.087],

Indexed as

Disease SusceptibilityAdultAlbuminuriaBiomarkersChinaFemaleHumansKidney Function TestsMaleMiddle AgedOdds RatioPopulation SurveillancePotassiumSodiumSodium Chloride, DietaryBiomarkersPotassiumSodiumSodium Chloride, Dietaryalbuminuriakidney functionpotassiumsodiumsodium-to-potassium ratio

Identifiers

PMID34684456
PMCPMC8539080
OpenAlexW3204925317

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.