Evidence map›Paper›PMID 34685476›Full record

ArticleLife (Basel, Switzerland)2021

The Circadian Rhythms of STAT3 in the Rat Pineal Gland and Its Involvement in Arylalkylamine-N-Acetyltransferase Regulation.

Simona Moravcová, Eva Filipovská, Veronika Spišská, Irena Svobodová, Jiří Novotný, Zdeňka Bendová

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Simona MoravcováDepartment of Physiology, Faculty of Science, Charles University, 128 43 Prague, Czech Republic.
Eva FilipovskáDepartment of Physiology, Faculty of Science, Charles University, 128 43 Prague, Czech Republic.ORCID 0000-0002-0789-7653
Veronika SpišskáDepartment of Physiology, Faculty of Science, Charles University, 128 43 Prague, Czech Republic.
Irena SvobodováLaboratory of Pain Research, Institute of Physiology, Academy of Sciences of the Czech Republic, 142 20 Prague, Czech Republic.
Jiří NovotnýDepartment of Physiology, Faculty of Science, Charles University, 128 43 Prague, Czech Republic.
Zdeňka BendováDepartment of Physiology, Faculty of Science, Charles University, 128 43 Prague, Czech Republic.ORCID 0000-0002-2693-2143
Charles University · CZCzech Academy of Sciences · CZ

Funding

European Regional Development Fund-Projects PharmaBrain" No. CZ.CZ.02.1.01/0.0/0.0/16_025/0007444Grantová Agentura České Republiky 18-08423SGrantová Agentura, Univerzita Karlova 1198218
6 · The paper itself

Abstract

In rodents, the melatonin production by the pineal gland is controlled through adrenergic signaling from the suprachiasmatic nuclei and regulation of the principal enzyme in its synthesis, arylalkylamine-N-acetyltransferase (AANAT). In the present study, we identified increased isoprenaline-induced

Indexed as

arylalkylamine-N-acetyltransferasecircadian rhythmslipopolysaccharidepineal glandratSTAT3

Identifiers

PMID34685476
PMCPMC8541109
OpenAlexW3207365046

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.