Evidence map›Paper›PMID 34685553›Full record

ReviewCells2021

Imaging Inflammation in Patients and Animals: Focus on PET Imaging the Vulnerable Plaque.

Benjamin Bartlett, Herbert P Ludewick, Silvia Lee, Shipra Verma, Roslyn J Francis, Girish Dwivedi

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Beyond the Lumen: Molecular Imaging to Unmask Vulnerable Coronary Plaques.Journal of cardiovascular development and disease · 2025
    Review
  3. Review
  4. Review
  5. In Vivo Detection ofInternational journal of biomedical imaging · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Benjamin BartlettDepartment of Advanced Clinical and Translational Cardiovascular Imaging, Harry Perkins Institute of Medical Research, Murdoch, WA 6150, Australia.
Herbert P LudewickDepartment of Advanced Clinical and Translational Cardiovascular Imaging, Harry Perkins Institute of Medical Research, Murdoch, WA 6150, Australia.
Silvia LeeDepartment of Advanced Clinical and Translational Cardiovascular Imaging, Harry Perkins Institute of Medical Research, Murdoch, WA 6150, Australia.ORCID 0000-0001-5405-9735
Shipra VermaDepartment of Nuclear Medicine, PET CT and Radionuclide Therapy, Fiona Stanley Hospital, Murdoch, WA 6150, Australia.
Roslyn J FrancisSchool of Medicine, University of Western Australia, Perth, WA 6009, Australia.
Girish DwivediDepartment of Advanced Clinical and Translational Cardiovascular Imaging, Harry Perkins Institute of Medical Research, Murdoch, WA 6150, Australia.ORCID 0000-0003-0717-740X
The University of Western Australia · AUHarry Perkins Institute of Medical Research · AUFiona Stanley Hospital · AU

Funding

Harry Perkins Institute of Medical Research N/A
6 · The paper itself

Abstract

Acute coronary syndrome (ACS) describes a range of conditions associated with the rupture of high-risk or vulnerable plaque. Vulnerable atherosclerotic plaque is associated with many changes in its microenvironment which could potentially cause rapid plaque progression. Present-day PET imaging presents a plethora of radiopharmaceuticals designed to image different characteristics throughout plaque progression. Improved knowledge of atherosclerotic disease pathways has facilitated a growing number of pathophysiological targets for more innovative radiotracer design aimed at identifying at-risk vulnerable plaque and earlier intervention opportunity. This paper reviews the efficacy of PET imaging radiotracers

Indexed as

AnimalsDisease Models, AnimalHumansInflammationMicePlaque, AtheroscleroticPositron-Emission TomographyatherosclerosisinflammationPET imagingvulnerable plaque

Identifiers

PMID34685553
PMCPMC8533866
OpenAlexW3203772642

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.