Evidence mapPaperPMID 34685697Full record

Observational studyCells2021

Effect of Perioperative Lipid Status on Clinical Outcomes after Cardiac Surgery.

Maks Mihalj, Paul Philipp Heinisch, Markus Huber, Joerg C Schefold, Alexander Hartmann, Michael Walter, Elisabeth Steinhagen-Thiessen, Juerg Schmidli, Frank Stüber, Lorenz Räber and 1 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Maks MihaljDepartment of Cardiovascular Surgery, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0000-0002-6298-7985
Paul Philipp HeinischDepartment of Cardiovascular Surgery, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.
Markus HuberDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0001-8081-0684
Joerg C SchefoldDepartment of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0001-9162-5724
Alexander HartmannInstitut für Klinische Chemie und Laboratoriumsmedizin, Universitätsmedizin Rostock, 18057 Rostock, Germany.
Michael WalterInstitut für Klinische Chemie und Laboratoriumsmedizin, Universitätsmedizin Rostock, 18057 Rostock, Germany.ORCID 0000-0003-4758-9716
Elisabeth Steinhagen-ThiessenInstitut für Klinische Chemie und Laboratoriumsmedizin, Universitätsmedizin Rostock, 18057 Rostock, Germany.
Juerg SchmidliDepartment of Cardiovascular Surgery, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0000-0001-6881-0956
Frank StüberDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Lorenz RäberDepartment of Cardiology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.
Markus M LuediDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-9049-2584
University of Bern · CHUniversitätsmedizin Rostock · DEUniversity Hospital of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients undergoing cardiac surgery are at increased cardiovascular risk, which includes altered lipid status. However, data on the effect of cardiac surgery and cardiopulmonary bypass (CPB) on plasma levels of key lipids are scarce. We investigated potential effects of CPB on plasma lipid levels and associations with early postoperative clinical outcomes. This is a prospective bio-bank study of patients undergoing elective cardiac surgery at our center January to December 2019. The follow-up period was 1 year after surgery. Blood sampling was performed before induction of general anesthesia, upon weaning from cardiopulmonary bypass (CPB), and on the first day after surgery. Clinical end points included the incidence of postoperative stroke, myocardial infarction, and death of any cause at 30 days after surgery as well as 1-year all-cause mortality. A total of 192 cardiac surgery patients (75% male, median age 67.0 years (interquartile range 60.0-73.0), median BMI 26.1 kg/m

Indexed as

Cardiac Surgical ProceduresPerioperative CareAgedEndpoint DeterminationFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLipidsMaleMiddle AgedOdds RatioPostoperative ComplicationsStrokeTime FactorsTreatment OutcomeHydroxymethylglutaryl-CoA Reductase InhibitorsLipidscardiac surgerycardiopulmonary bypasscholesterolHDLLDLlipidtriglycerides

Identifiers

PMID34685697
PMCPMC8534806
OpenAlexW3205335734

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.