Evidence mapPaperPMID 34687329Full record

ReviewAbdominal radiology (New York)2022

Liver fibrosis assessment: MR and US elastography.

Arinc Ozturk, Michael C Olson, Anthony E Samir, Sudhakar K Venkatesh

Open access · greenAbstract readReview
In one paragraph

Review in Abdominal radiology (New York), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 3 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 3 syntheses or guidelines pooled it, 144 citations in OpenAlex.

  1. Pooled it
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  13. [Novel advances following the integration of Baveno VII consensus definitions for the non-invasive testing of portal hypertension].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Review
  14. Clinical feasibility of accelerated whole liver water TEuropean radiology experimental · 2026
    Article
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Arinc Ozturk *Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Michael C Olson *Division of Abdominal Imaging, Radiology, Mayo Clinic Rochester, 200, First Street SW, Rochester, MN, 55905, USA.
Anthony E Samir *Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Sudhakar K Venkatesh *Division of Abdominal Imaging, Radiology, Mayo Clinic Rochester, 200, First Street SW, Rochester, MN, 55905, USA. venkatesh.sudhakar@mayo.edu.ORCID http://orcid.org/0000-0002-7514-1030
Massachusetts General Hospital · USMayo Clinic · US

Funding

Magnetic Resonance ElastographyR37EB001981 · NIBIB · MAYO CLINIC ROCHESTER · 2022 to 2025
$1.6M
Magnetic Resonance ElastographyR01EB001981 · MAYO CLINIC COLL OF MEDICINE, ROCHESTER · 2003 to 2005
$1.1M
Development of a Machine Learning Model to Integrate Clinical, Laboratory, Sonographic, and Elastographic Data for Noninvasive Liver Tissue Characterization in NAFLDR01DK119860 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Anthony Edward Samir · 2022 to 2023
$897k
NIBIB NIH HHS R01 EB001981NIBIB NIH HHS R37 EB001981NIDDK NIH HHS R01 DK119860
6 · The paper itself

Abstract

Elastography has emerged as a preferred non-invasive imaging technique for the clinical assessment of liver fibrosis. Elastography methods provide liver stiffness measurement (LSM) as a surrogate quantitative biomarker for fibrosis burden in chronic liver disease (CLD). Elastography can be performed either with ultrasound or MRI. Currently available ultrasound-based methods include strain elastography, two-dimensional shear wave elastography (2D-SWE), point shear wave elastography (pSWE), and vibration-controlled transient elastography (VCTE). MR Elastography (MRE) is widely available as two-dimensional gradient echo MRE (2D-GRE-MRE) technique. US-based methods provide estimated Young's modulus (eYM) and MRE provides magnitude of the complex shear modulus. MRE and ultrasound methods have proven to be accurate methods for detection of advanced liver fibrosis and cirrhosis. Other clinical applications of elastography include liver decompensation prediction, and differentiation of non-alcoholic steatohepatitis (NASH) from simple steatosis (SS). In this review, we briefly describe the different elastography methods, discuss current clinical applications, and provide an overview of advances in the field of liver elastography.

Indexed as

Elasticity Imaging TechniquesNon-alcoholic Fatty Liver DiseaseHumansLiverLiver CirrhosisMagnetic Resonance ImagingChronic liver diseaseFibrosis stagingLiver stiffnessNon-alcoholic steatohepatitisShear stiffness

Identifiers

PMID34687329
PMCPMC9033887
OpenAlexW3205123223

What Socratic holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.